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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+7.99%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$171M
AUM Growth
-$80.3M
Cap. Flow
-$96.1M
Cap. Flow %
-56.34%
Top 10 Hldgs %
95.55%
Holding
509
New
8
Increased
62
Reduced
141
Closed
9

Top Buys

Rank Stock Value
1
APP icon
Applovin
APP
+$26.7K
2
HOOD icon
Robinhood
HOOD
+$18.1K
3
AMZN icon
Amazon
AMZN
+$10.2K
4
DDOG icon
Datadog
DDOG
+$9.5K
5
XYZ
Block Inc
XYZ
+$8.91K

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$96.2M
2
AAPL icon
Apple
AAPL
+$9.94K
3
HES
Hess
HES
+$8.17K
4
NVDA icon
NVIDIA
NVDA
+$7.84K
5
MSFT icon
Microsoft
MSFT
+$7.14K

Sector Composition

Rank Sector Weight
1 Technology 2.56%
2 Financials 0.95%
3 Consumer Discretionary 0.76%
4 Communication Services 0.75%
5 Healthcare 0.64%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PTC icon
326
PTC
PTC
$16.1B
$5.28K ﹤0.01%
26
– –
IP icon
327
International Paper
IP
$21.8B
$5.24K ﹤0.01%
113
– –
CINF icon
328
Cincinnati Financial
CINF
$26.5B
$5.22K ﹤0.01%
33
– –
STE icon
329
Steris
STE
$23.1B
$5.2K ﹤0.01%
21
– –
SMCI icon
330
Super Micro Computer
SMCI
$24.3B
$5.18K ﹤0.01%
108
– –
LH icon
331
Labcorp
LH
$26.2B
$5.17K ﹤0.01%
18
– –
PPG icon
332
PPG Industries
PPG
$25.5B
$5.15K ﹤0.01%
49
-1
-2% -$111
NTAP icon
333
NetApp
NTAP
$39.6B
$5.09K ﹤0.01%
43
– –
FE icon
334
FirstEnergy
FE
$27.2B
$5.09K ﹤0.01%
111
+1
+0.9% +$43
WSM icon
335
Williams-Sonoma
WSM
$28.9B
$5.08K ﹤0.01%
26
– –
FSLR icon
336
First Solar
FSLR
$24.4B
$5.07K ﹤0.01%
23
– –
RF icon
337
Regions Financial
RF
$26.9B
$5.06K ﹤0.01%
192
-4
-2% -$104
VRSN icon
338
VeriSign
VRSN
$25.6B
$5.03K ﹤0.01%
18
+1
+6% +$279
JBL icon
339
Jabil
JBL
$38.4B
$5K ﹤0.01%
23
– –
TPR icon
340
Tapestry
TPR
$31.1B
$4.98K ﹤0.01%
44
– –
CFG icon
341
Citizens Financial Group
CFG
$31.1B
$4.94K ﹤0.01%
93
-1
-1% -$50
TROW icon
342
T. Rowe Price
TROW
$23.8B
$4.93K ﹤0.01%
48
– –
MTD icon
343
Mettler-Toledo International
MTD
$28.8B
$4.91K ﹤0.01%
4
– –
WRB icon
344
W.R. Berkley
WRB
$25.9B
$4.9K ﹤0.01%
64
– –
DG icon
345
Dollar General
DG
$26.4B
$4.86K ﹤0.01%
47
– –
DOV icon
346
Dover
DOV
$28B
$4.84K ﹤0.01%
29
– –
TER icon
347
Teradyne
TER
$63B
$4.82K ﹤0.01%
35
– –
DVN icon
348
Devon Energy
DVN
$49.3B
$4.8K ﹤0.01%
137
-4
-3% -$136
KHC icon
349
Kraft Heinz
KHC
$29.1B
$4.79K ﹤0.01%
184
-4
-2% -$109
EQR icon
350
Equity Residential
EQR
$24.2B
$4.79K ﹤0.01%
74
+1
+1% +$65
12 13
14
15 16

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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q3 2025 Portfolio in Review

As of Q3 2025, Howard Hughes Medical Institute held 509 positions worth $171M, down 32% from $251M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Howard Hughes Medical Institute withdrew a net $96.1M in Q3 2025, closing 9 positions and reducing 141 holdings. Its most notable exit was Hess, an estimated $8.17K position sold in full.

By sector, the portfolio is most concentrated in Technology at 2.6% of assets, up from 1.6% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Howard Hughes Medical Institute opened a new position in Applovin worth $41.7K.

  • Howard Hughes Medical Institute's largest Q3 2025 buy was Applovin: 58 shares worth $41.7K.
  • Howard Hughes Medical Institute added most to Amazon in Q3 2025, an estimated $10.2K increase.
  • Howard Hughes Medical Institute's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $96.2M.
  • Howard Hughes Medical Institute fully exited Hess in Q3 2025, selling an estimated $8.17K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $171M portfolio in Q3 2025.
  • Howard Hughes Medical Institute opened 8 new positions and closed 9 in Q3 2025.
  • Howard Hughes Medical Institute's portfolio value fell 32% quarter-over-quarter to $171M.

Based on Howard Hughes Medical Institute's 13F filing for Q3 2025, filed 14 Nov 2025.