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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MLM icon
251
Martin Marietta Materials
MLM
$32.7B
$8.1K ﹤0.01%
13
GEHC icon
252
GE HealthCare
GEHC
$32.6B
$8.04K ﹤0.01%
98
VMC icon
253
Vulcan Materials
VMC
$36.3B
$7.99K ﹤0.01%
28
STT icon
254
State Street
STT
$52.2B
$7.87K ﹤0.01%
61
UAL icon
255
United Airlines
UAL
$40.6B
$7.83K ﹤0.01%
70
VTR icon
256
Ventas
VTR
$45.7B
$7.82K ﹤0.01%
101
+4
+4% +$302
FISV
257
Fiserv Inc
FISV
$27.4B
$7.79K ﹤0.01%
116
-1
-0.9% -$84
PAYX icon
258
Paychex
PAYX
$42.8B
$7.74K ﹤0.01%
69
WAB icon
259
Wabtec
WAB
$49.9B
$7.68K ﹤0.01%
36
XYZ
260
Block Inc
XYZ
$47B
$7.68K ﹤0.01%
118
-1
-0.8% -$69
ED icon
261
Consolidated Edison
ED
$39.9B
$7.65K ﹤0.01%
77
PCG icon
262
PG&E
PCG
$38.3B
$7.62K ﹤0.01%
474
+2
+0.4% +$32
SYY icon
263
Sysco
SYY
$40.5B
$7.59K ﹤0.01%
103
KEYS icon
264
Keysight
KEYS
$60.6B
$7.52K ﹤0.01%
37
ACGL icon
265
Arch Capital
ACGL
$33.2B
$7.48K ﹤0.01%
78
-2
-3% -$183
CPRT icon
266
Copart
CPRT
$26.8B
$7.48K ﹤0.01%
191
RMD icon
267
ResMed
RMD
$32.8B
$7.47K ﹤0.01%
31
FIS icon
268
Fidelity National Information Services
FIS
$21.6B
$7.44K ﹤0.01%
112
-1
-0.9% -$66
MCHP icon
269
Microchip Technology
MCHP
$43.1B
$7.39K ﹤0.01%
116
WEC icon
270
WEC Energy
WEC
$35.6B
$7.38K ﹤0.01%
70
+1
+1% +$111
EXPE icon
271
Expedia Group
EXPE
$39.1B
$7.37K ﹤0.01%
26
OTIS icon
272
Otis Worldwide
OTIS
$28.2B
$7.34K ﹤0.01%
84
-1
-1% -$89
EQT icon
273
EQT Corp
EQT
$33.8B
$7.18K ﹤0.01%
134
KMB icon
274
Kimberly-Clark
KMB
$36.2B
$7.16K ﹤0.01%
71
KVUE icon
275
Kenvue
KVUE
$36.5B
$7.12K ﹤0.01%
413

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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.