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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
251
Wabtec
WAB
$49.9B
| $7.54K | ﹤0.01% |
+36
| New | +$6.92K |
|
252
EQT Corp
EQT
$33.8B
| $7.46K | ﹤0.01% |
+128
| New | +$6.91K |
|
253
Consolidated Edison
ED
$39.9B
| $7.43K | ﹤0.01% |
+74
| New | +$7.83K |
|
254
VICI Properties
VICI
$28.7B
| $7.4K | ﹤0.01% |
+227
| New | +$7.22K |
|
255
Arch Capital
ACGL
$33.2B
| $7.38K | ﹤0.01% |
+81
| New | +$7.47K |
|
256
DexCom
DXCM
$34.3B
| $7.33K | ﹤0.01% |
+84
| New | +$6.58K |
|
257
CoStar Group
CSGP
$12.4B
| $7.32K | ﹤0.01% |
+91
| New | +$7.09K |
|
258
Monolithic Power Systems
MPWR
$70B
| $7.31K | ﹤0.01% |
+10
| New | +$6.37K |
|
259
Vulcan Materials
VMC
$36.3B
| $7.3K | ﹤0.01% |
+28
| New | +$7.2K |
|
260
GE HealthCare
GEHC
$32.6B
| $7.26K | ﹤0.01% |
+98
| New | +$6.82K |
|
261
Ingersoll Rand
IR
$32.9B
| $7.24K | ﹤0.01% |
+87
| New | +$6.86K |
|
262
Agilent Technologies
A
$41.9B
| $7.2K | ﹤0.01% |
+61
| New | +$6.76K |
|
263
Martin Marietta Materials
MLM
$32.7B
| $7.14K | ﹤0.01% |
+13
| New | +$6.87K |
|
264
WEC Energy
WEC
$35.6B
| $7.09K | ﹤0.01% |
+68
| New | +$7.24K |
|
265
NRG Energy
NRG
$25.4B
| $6.91K | ﹤0.01% |
+43
| New | +$5.67K |
|
|
GRMN
266
Garmin
GRMN
$59.8B
| $6.89K | ﹤0.01% |
+33
| New | +$6.55K |
|
267
M&T Bank
MTB
$36.6B
| $6.79K | ﹤0.01% |
+35
| New | +$6.18K |
|
268
Delta Air Lines
DAL
$59.1B
| $6.79K | ﹤0.01% |
+138
| New | +$6.34K |
|
269
Equifax
EFX
$21.2B
| $6.74K | ﹤0.01% |
+26
| New | +$6.61K |
|
270
Xylem
XYL
$28.5B
| $6.73K | ﹤0.01% |
+52
| New | +$6.3K |
|
271
Extra Space Storage
EXR
$31B
| $6.63K | ﹤0.01% |
+45
| New | +$6.55K |
|
272
PG&E
PCG
$38.3B
| $6.62K | ﹤0.01% |
+475
| New | +$7.73K |
|
273
State Street
STT
$52.2B
| $6.59K | ﹤0.01% |
+62
| New | +$5.73K |
|
274
Seagate
STX
$199B
| $6.5K | ﹤0.01% |
+45
| New | +$4.66K |
|
275
Old Dominion Freight Line
ODFL
$44.1B
| $6.49K | ﹤0.01% |
+40
| New | +$6.38K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.