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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ROK icon
226
Rockwell Automation
ROK
$50.1B
$9.34K 0.01%
24
– –
MSCI icon
227
MSCI
MSCI
$40.9B
$9.18K 0.01%
16
– –
RSG icon
228
Republic Services
RSG
$65.6B
$9.11K 0.01%
43
– –
AXON
229
Axon Enterprise
AXON
$48.7B
$9.09K 0.01%
16
– –
GWW icon
230
W.W. Grainger
GWW
$61.5B
$9.08K 0.01%
9
– –
YUM icon
231
Yum! Brands
YUM
$41B
$9.08K 0.01%
60
– –
MPWR icon
232
Monolithic Power Systems
MPWR
$70B
$9.06K 0.01%
10
– –
CARR icon
233
Carrier Global
CARR
$52B
$9.04K 0.01%
171
-1
-0.6% -$56
ETR icon
234
Entergy
ETR
$50.3B
$8.87K 0.01%
96
+1
+1% +$95
PSA icon
235
Public Storage
PSA
$60.4B
$8.82K 0.01%
34
– –
TRGP icon
236
Targa Resources
TRGP
$57.6B
$8.67K 0.01%
47
– –
CTSH icon
237
Cognizant
CTSH
$26.2B
$8.63K ﹤0.01%
104
-1
-1% -$75
PEG icon
238
Public Service Enterprise Group
PEG
$37.8B
$8.59K ﹤0.01%
107
– –
PRU icon
239
Prudential Financial
PRU
$42.3B
$8.58K ﹤0.01%
76
– –
EBAY icon
240
eBay
EBAY
$45.5B
$8.54K ﹤0.01%
98
-1
-1% -$87
DHI icon
241
D.R. Horton
DHI
$40.8B
$8.5K ﹤0.01%
59
-1
-2% -$152
FICO icon
242
Fair Isaac
FICO
$22.6B
$8.45K ﹤0.01%
5
– –
HIG icon
243
Hartford Financial Services
HIG
$37.7B
$8.41K ﹤0.01%
61
– –
DELL icon
244
Dell
DELL
$313B
$8.31K ﹤0.01%
66
– –
A icon
245
Agilent Technologies
A
$41.9B
$8.3K ﹤0.01%
61
– –
CCI icon
246
Crown Castle
CCI
$31.5B
$8.27K ﹤0.01%
93
– –
KR icon
247
Kroger
KR
$34.3B
$8.19K ﹤0.01%
131
– –
KDP icon
248
Keurig Dr Pepper
KDP
$40.2B
$8.18K ﹤0.01%
292
– –
NUE icon
249
Nucor
NUE
$61.9B
$8.16K ﹤0.01%
50
– –
IQV icon
250
IQVIA
IQV
$39.8B
$8.12K ﹤0.01%
36
– –
8 9
10
11 12

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SSC
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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.