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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+5.08%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$126M
AUM Growth
-$25.5M
Cap. Flow
-$24.9M
Cap. Flow %
-19.84%
Top 10 Hldgs %
47.53%
Holding
143
New
16
Increased
24
Reduced
11
Closed
74

Top Buys

Rank Stock Value
1
COHR
Coherent Inc
COHR
+$3.51M
2
PBCT
People's United Financial Inc
PBCT
+$3.5M
3
CONE
CyrusOne Inc Common Stock
CONE
+$3.28M
4
FULC icon
Fulcrum Therapeutics
FULC
+$1.78M
5
IVVD icon
Invivyd
IVVD
+$1.69M

Top Sells

Rank Stock Value
1
DELL icon
Dell
DELL
+$19.3M
2
PPD
PPD, Inc. Common Stock
PPD
+$3.5M
3
KSU
Kansas City Southern
KSU
+$3.49M
4
SMIN icon
iShares MSCI India Small-Cap ETF
SMIN
+$3.15M
5
FIVN icon
FIVE9
FIVN
+$2.78M

Sector Composition

Rank Sector Weight
1 Healthcare 52.52%
2 Technology 21.51%
3 Consumer Discretionary 5.99%
4 Communication Services 3.46%
5 Financials 2.78%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DELL icon
1
Dell
DELL
$262B
$20M 15.89%
355,444
-345,847
-49% -$19.3M
CPNG icon
2
Coupang
CPNG
$28.9B
$7.53M 5.99%
256,264
– –
XLNX
3
DELISTED
Xilinx Inc
XLNX
$5.13M 4.08%
24,173
– –
MSDAU
4
DELISTED
MSD Acquisition Corp. Unit
MSDAU
$5.08M 4.04%
500,000
– –
INFO
5
DELISTED
IHS Markit Ltd. Common Shares
INFO
$4.35M 3.46%
32,743
– –
COHR
6
DELISTED
Coherent Inc
COHR
$3.63M 2.89%
+13,600
New +$3.51M
NUAN
7
DELISTED
Nuance Communications, Inc.
NUAN
$3.59M 2.86%
64,841
– –
PBCT
8
DELISTED
People's United Financial Inc
PBCT
$3.5M 2.78%
+196,100
New +$3.5M
CONE
9
DELISTED
CyrusOne Inc Common Stock
CONE
$3.47M 2.76%
+38,700
New +$3.28M
CHNG
10
DELISTED
Change Healthcare Inc. Common Stock
CHNG
$3.47M 2.76%
162,100
– –
CPARU
11
DELISTED
Catalyst Partners Acquisition Corp. Unit
CPARU
$2M 1.59%
200,000
– –
ARNA
12
DELISTED
Arena Pharmaceuticals Inc
ARNA
$1.99M 1.59%
21,433
-2,425
-10% -$160K
XENE icon
13
Xenon Pharmaceuticals
XENE
$6.2B
$1.97M 1.56%
62,906
-12,140
-16% -$363K
ARGX icon
14
argenx
ARGX
$54.6B
$1.95M 1.55%
5,562
+1,855
+50% +$564K
MRUS
15
DELISTED
Merus
MRUS
$1.71M 1.36%
+53,840
New +$1.52M
ISEE
16
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$1.69M 1.35%
101,144
+38,037
+60% +$623K
TVTX icon
17
Travere Therapeutics
TVTX
$5.33B
$1.68M 1.34%
54,103
-2,591
-5% -$73K
ACRS icon
18
Aclaris Therapeutics
ACRS
$743M
$1.63M 1.3%
112,160
+19,160
+21% +$290K
CYTK icon
19
Cytokinetics
CYTK
$10.9B
$1.61M 1.28%
+35,232
New +$1.36M
ITOS
20
DELISTED
iTeos Therapeutics
ITOS
$1.61M 1.28%
+34,487
New +$1.15M
FULC icon
21
Fulcrum Therapeutics
FULC
$248M
$1.59M 1.27%
+89,963
New +$1.78M
CRNX icon
22
Crinetics Pharmaceuticals
CRNX
$8.85B
$1.5M 1.2%
+52,982
New +$1.31M
BPMC
23
DELISTED
Blueprint Medicines
BPMC
$1.48M 1.18%
13,843
+1,127
+9% +$118K
GRTS
24
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
$1.46M 1.16%
113,752
+99,299
+687% +$1.1M
RLAY icon
25
Relay Therapeutics
RLAY
$4.24B
$1.41M 1.12%
45,992
+8,249
+22% +$261K
1
2 3 4 5

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HighVista Strategies's Q4 2021 Portfolio in Review

As of Q4 2021, HighVista Strategies held 143 positions worth $126M, down 17% from $151M the previous quarter. Its ten largest holdings account for 48% of the portfolio.

HighVista Strategies withdrew a net $24.9M in Q4 2021, closing 74 positions and reducing 11 holdings. Its most notable exit was PPD, Inc. Common Stock, an estimated $3.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 53% of assets, up from 44% a quarter earlier, followed by Technology and Consumer Discretionary.

Against the trend, HighVista Strategies opened a new position in Coherent Inc worth $3.63M.

  • HighVista Strategies's largest Q4 2021 buy was Coherent Inc: 13,600 shares worth $3.63M.
  • HighVista Strategies added most to Gritstone bio, Inc. Common Stock in Q4 2021, an estimated $1.1M increase.
  • HighVista Strategies's biggest Q4 2021 reduction was Dell, cutting an estimated $19.3M.
  • HighVista Strategies fully exited PPD, Inc. Common Stock in Q4 2021, selling an estimated $3.5M.
  • HighVista Strategies's ten largest holdings make up 48% of its $126M portfolio in Q4 2021.
  • HighVista Strategies opened 16 new positions and closed 74 in Q4 2021.
  • HighVista Strategies's portfolio value fell 17% quarter-over-quarter to $126M.

Based on HighVista Strategies's 13F filing for Q4 2021, filed 14 Feb 2022.