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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
-4.54%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$260M
AUM Growth
-$9.28M
Cap. Flow
+$13.5M
Cap. Flow %
5.19%
Top 10 Hldgs %
25.84%
Holding
172
New
35
Increased
39
Reduced
27
Closed
24

Top Buys

Rank Stock Value
1
PWR icon
Quanta Services
PWR
+$2.34M
2
MTZ icon
MasTec
MTZ
+$2.2M
3
MA icon
Mastercard
MA
+$2.01M
4
IMVT icon
Immunovant
IMVT
+$2M
5
MMM icon
3M
MMM
+$1.98M

Top Sells

Rank Stock Value
1
HCP
HashiCorp, Inc. Class A Common Stock
HCP
+$4.45M
2
AMZN icon
Amazon
AMZN
+$3.36M
3
TEVA icon
Teva Pharmaceuticals
TEVA
+$2.23M
4
LYV icon
Live Nation Entertainment
LYV
+$2.02M
5
GH icon
Guardant Health
GH
+$1.83M

Sector Composition

Rank Sector Weight
1 Healthcare 39.15%
2 Technology 17.75%
3 Industrials 8.61%
4 Consumer Discretionary 6.17%
5 Financials 5%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BCYC
151
Bicycle Therapeutics
BCYC
$288M
– –
-124,430
Closed -$1.74M
CZR icon
152
Caesars Entertainment
CZR
$6.06B
– –
-35,200
Closed -$1.18M
DIS icon
153
Walt Disney
DIS
$179B
– –
-11,200
Closed -$1.25M
FCNCA icon
154
First Citizens BancShares
FCNCA
$25.4B
– –
-600
Closed -$1.27M
FIS icon
155
Fidelity National Information Services
FIS
$22.1B
– –
-16,400
Closed -$1.32M
IDYA icon
156
IDEAYA Biosciences
IDYA
$3.55B
– –
-47,728
Closed -$1.23M
INDV icon
157
Indivior Pharmaceuticals
INDV
$4.54B
– –
-142,634
Closed -$1.83M
KRYS icon
158
Krystal Biotech
KRYS
$9.68B
– –
-4,217
Closed -$661K
KURA icon
159
Kura Oncology
KURA
$882M
– –
-46,181
Closed -$402K
LAUR icon
160
Laureate Education
LAUR
$5.05B
– –
-72,107
Closed -$1.32M
LYV icon
161
Live Nation Entertainment
LYV
$42.7B
– –
-15,600
Closed -$2.02M
STNE icon
162
StoneCo
STNE
$2.42B
– –
-168,330
Closed -$1.34M
TERN
163
DELISTED
Terns Pharmaceuticals
TERN
– –
-130,966
Closed -$726K
TEVA icon
164
Teva Pharmaceuticals
TEVA
$42.5B
– –
-101,300
Closed -$2.23M
TMUS icon
165
T-Mobile US
TMUS
$192B
– –
-5,800
Closed -$1.28M
UBER icon
166
Uber
UBER
$160B
– –
-21,700
Closed -$1.31M
UPWK icon
167
Upwork
UPWK
$1.03B
– –
-83,600
Closed -$1.37M
VST icon
168
Vistra
VST
$48.6B
– –
-9,600
Closed -$1.32M
WMG icon
169
Warner Music
WMG
$13.1B
– –
-47,000
Closed -$1.46M
WRBY icon
170
Warby Parker
WRBY
$3.1B
– –
-62,000
Closed -$1.5M
ITCI
171
DELISTED
Intra-Cellular Therapies Inc.
ITCI
– –
-7,496
Closed -$626K
HCP
172
DELISTED
HashiCorp, Inc. Class A Common Stock
HCP
– –
-130,200
Closed -$4.45M
3 4 5 6
7

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ACM
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HighVista Strategies's Q1 2025 Portfolio in Review

As of Q1 2025, HighVista Strategies held 172 positions worth $260M, down 3.5% from $269M the previous quarter. Its ten largest holdings account for 26% of the portfolio.

HighVista Strategies deployed $13.5M of net new capital in Q1 2025, opening 35 new positions and adding to 39 existing holdings. Its largest new stake was Quanta Services: 8,100 shares worth $2.06M.

By sector, the portfolio is most concentrated in Healthcare at 39% of assets, down from 44% a quarter earlier, followed by Technology and Industrials.

On the sell side, the largest reduction was Amazon, an estimated $3.36M trimmed.

  • HighVista Strategies's largest Q1 2025 buy was Quanta Services: 8,100 shares worth $2.06M.
  • HighVista Strategies added most to Praxis Precision Medicines in Q1 2025, an estimated $1.77M increase.
  • HighVista Strategies's biggest Q1 2025 reduction was Amazon, cutting an estimated $3.36M.
  • HighVista Strategies fully exited HashiCorp, Inc. Class A Common Stock in Q1 2025, selling an estimated $4.45M.
  • HighVista Strategies's ten largest holdings make up 26% of its $260M portfolio in Q1 2025.
  • HighVista Strategies opened 35 new positions and closed 24 in Q1 2025.
  • HighVista Strategies's portfolio value fell 3.5% quarter-over-quarter to $260M.

Based on HighVista Strategies's 13F filing for Q1 2025, filed 15 May 2025.