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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+5.08%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$126M
AUM Growth
-$25.5M
Cap. Flow
-$24.9M
Cap. Flow %
-19.84%
Top 10 Hldgs %
47.53%
Holding
143
New
16
Increased
24
Reduced
11
Closed
74

Top Buys

Rank Stock Value
1
COHR
Coherent Inc
COHR
+$3.51M
2
PBCT
People's United Financial Inc
PBCT
+$3.5M
3
CONE
CyrusOne Inc Common Stock
CONE
+$3.28M
4
FULC icon
Fulcrum Therapeutics
FULC
+$1.78M
5
IVVD icon
Invivyd
IVVD
+$1.69M

Top Sells

Rank Stock Value
1
DELL icon
Dell
DELL
+$19.3M
2
PPD
PPD, Inc. Common Stock
PPD
+$3.5M
3
KSU
Kansas City Southern
KSU
+$3.49M
4
SMIN icon
iShares MSCI India Small-Cap ETF
SMIN
+$3.15M
5
FIVN icon
FIVE9
FIVN
+$2.78M

Sector Composition

Rank Sector Weight
1 Healthcare 52.52%
2 Technology 21.51%
3 Consumer Discretionary 5.99%
4 Communication Services 3.46%
5 Financials 2.78%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SEI
126
Solaris Energy Infrastructure
SEI
$3.85B
– –
-14,247
Closed -$119K
CMRX
127
DELISTED
Chimerix, Inc.
CMRX
– –
-15,212
Closed -$94K
CNSL
128
DELISTED
Consolidated Communications Holdings, Inc.
CNSL
– –
-11,981
Closed -$110K
VBIV
129
DELISTED
VBI Vaccines, Inc. New Common Stock (Canada)
VBIV
– –
-1,376
Closed -$129K
ALPN
130
DELISTED
Alpine Immune Sciences Inc
ALPN
– –
-14,268
Closed -$152K
IMGN
131
DELISTED
Immunogen Inc
IMGN
– –
-24,088
Closed -$137K
ONCT
132
DELISTED
Oncternal Therapeutics, Inc. Common Stock
ONCT
– –
-1,156
Closed -$97K
PCTI
133
DELISTED
PCTEL, Inc. Common Stock
PCTI
– –
-12,188
Closed -$75K
PRTK
134
DELISTED
Paratek Pharmaceuticals, Inc.
PRTK
– –
-19,182
Closed -$93K
SURF
135
DELISTED
Surface Oncology, Inc. Common Stock
SURF
– –
-13,932
Closed -$105K
SMED
136
DELISTED
Sharps Compliance Corp
SMED
– –
-11,206
Closed -$92K
NPTN
137
DELISTED
NEOPHOTONICS CORP
NPTN
– –
-10,633
Closed -$92K
KSU
138
DELISTED
Kansas City Southern
KSU
– –
-12,910
Closed -$3.49M
PPD
139
DELISTED
PPD, Inc. Common Stock
PPD
– –
-74,900
Closed -$3.5M
ADMS
140
DELISTED
Adamas Pharmaceuticals
ADMS
– –
-21,193
Closed -$104K
XLRN
141
DELISTED
Acceleron Pharma
XLRN
– –
-9,777
Closed -$1.68M
ESTE
142
DELISTED
Earthstone Energy Inc. Class A Common Stock
ESTE
– –
-15,639
Closed -$144K
LJPC
143
DELISTED
La Jolla Pharmaceutical Company
LJPC
– –
-25,493
Closed -$102K
2 3 4 5
6

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HighVista Strategies's Q4 2021 Portfolio in Review

As of Q4 2021, HighVista Strategies held 143 positions worth $126M, down 17% from $151M the previous quarter. Its ten largest holdings account for 48% of the portfolio.

HighVista Strategies withdrew a net $24.9M in Q4 2021, closing 74 positions and reducing 11 holdings. Its most notable exit was PPD, Inc. Common Stock, an estimated $3.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 53% of assets, up from 44% a quarter earlier, followed by Technology and Consumer Discretionary.

Against the trend, HighVista Strategies opened a new position in Coherent Inc worth $3.63M.

  • HighVista Strategies's largest Q4 2021 buy was Coherent Inc: 13,600 shares worth $3.63M.
  • HighVista Strategies added most to Gritstone bio, Inc. Common Stock in Q4 2021, an estimated $1.1M increase.
  • HighVista Strategies's biggest Q4 2021 reduction was Dell, cutting an estimated $19.3M.
  • HighVista Strategies fully exited PPD, Inc. Common Stock in Q4 2021, selling an estimated $3.5M.
  • HighVista Strategies's ten largest holdings make up 48% of its $126M portfolio in Q4 2021.
  • HighVista Strategies opened 16 new positions and closed 74 in Q4 2021.
  • HighVista Strategies's portfolio value fell 17% quarter-over-quarter to $126M.

Based on HighVista Strategies's 13F filing for Q4 2021, filed 14 Feb 2022.