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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+13.28%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$168M
AUM Growth
-$6.63M
Cap. Flow
-$14M
Cap. Flow %
-8.3%
Top 10 Hldgs %
40.66%
Holding
139
New
26
Increased
28
Reduced
31
Closed
34

Top Buys

Rank Stock Value
1
SJI
South Jersey Industries, Inc.
SJI
+$2.75M
2
AXSM icon
Axsome Therapeutics
AXSM
+$2.29M
3
THRD
Third Harmonic Bio
THRD
+$1.54M
4
ISEE
IVERIC bio, Inc. Common Stock
ISEE
+$1.37M
5
DICE
DICE Therapeutics, Inc. Common Stock
DICE
+$1.27M

Top Sells

Rank Stock Value
1
CHNG
Change Healthcare Inc. Common Stock
CHNG
+$4.46M
2
CYTK icon
Cytokinetics
CYTK
+$3.54M
3
CTXS
Citrix Systems Inc
CTXS
+$3.26M
4
NLSN
Nielsen Holdings plc
NLSN
+$3.17M
5
TWTR
Twitter, Inc.
TWTR
+$2.81M

Sector Composition

Rank Sector Weight
1 Healthcare 46.64%
2 Technology 19.92%
3 Financials 17.76%
4 Consumer Discretionary 3.48%
5 Communication Services 2.68%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TJX icon
101
TJX Companies
TJX
$172B
$210K 0.12%
+2,640
New +$195K
GOSS icon
102
Gossamer Bio
GOSS
$88.9M
$210K 0.12%
96,795
– –
PRMW
103
DELISTED
Primo Water Corporation
PRMW
$203K 0.12%
+13,060
New +$190K
LBTYA icon
104
Liberty Global Class A
LBTYA
$3.48B
$199K 0.12%
+10,510
New +$191K
RLMD icon
105
Relmada Therapeutics
RLMD
$477M
$91.8K 0.05%
26,299
-3,764
-13% -$33.1K
ADSK icon
106
Autodesk
ADSK
$53.1B
– –
-1,766
Closed -$330K
BCRX icon
107
BioCryst Pharmaceuticals
BCRX
$2.64B
– –
-25,837
Closed -$326K
BEAM icon
108
Beam Therapeutics
BEAM
$2.77B
– –
-12,584
Closed -$600K
CYTK icon
109
Cytokinetics
CYTK
$10.6B
– –
-73,154
Closed -$3.54M
DDOG icon
110
Datadog
DDOG
$88.6B
– –
-2,310
Closed -$205K
DSGN icon
111
Design Therapeutics
DSGN
$915M
– –
-38,152
Closed -$638K
DUOL icon
112
Duolingo
DUOL
$6.34B
– –
-2,096
Closed -$200K
ENTA icon
113
Enanta Pharmaceuticals
ENTA
$393M
– –
-11,286
Closed -$585K
IOVA icon
114
Iovance Biotherapeutics
IOVA
$2.94B
– –
-72,104
Closed -$691K
IQ icon
115
iQIYI
IQ
$1.3B
– –
-37,518
Closed -$102K
LNG icon
116
Cheniere Energy
LNG
$54.8B
– –
-1,406
Closed -$233K
MDGL icon
117
Madrigal Pharmaceuticals
MDGL
$12.4B
– –
-9,527
Closed -$619K
MRUS
118
DELISTED
Merus
MRUS
– –
-36,994
Closed -$741K
NBIX icon
119
Neurocrine Biosciences
NBIX
$16.5B
– –
-8,373
Closed -$889K
PMVP icon
120
PMV Pharmaceuticals
PMVP
$69.3M
– –
-23,324
Closed -$278K
RGNX icon
121
Regenxbio
RGNX
$703M
– –
-29,696
Closed -$785K
RIVN icon
122
Rivian
RIVN
$23.7B
– –
-6,364
Closed -$209K
RNAM
123
DELISTED
Avidity Biosciences
RNAM
– –
-17,334
Closed -$283K
RVMD icon
124
Revolution Medicines
RVMD
$44.1B
– –
-42,056
Closed -$829K
TEAM icon
125
Atlassian
TEAM
$39.1B
– –
-1,178
Closed -$248K
2 3 4
5
6

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HighVista Strategies's Q4 2022 Portfolio in Review

As of Q4 2022, HighVista Strategies held 139 positions worth $168M, down 3.8% from $175M the previous quarter. Its ten largest holdings account for 41% of the portfolio.

HighVista Strategies withdrew a net $14M in Q4 2022, closing 34 positions and reducing 31 holdings. Its most notable exit was Change Healthcare Inc. Common Stock, an estimated $4.46M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 47% of assets, up from 46% a quarter earlier, followed by Technology and Financials.

Against the trend, HighVista Strategies opened a new position in South Jersey Industries, Inc. worth $2.82M.

  • HighVista Strategies's largest Q4 2022 buy was South Jersey Industries, Inc.: 79,500 shares worth $2.82M.
  • HighVista Strategies added most to Axsome Therapeutics in Q4 2022, an estimated $2.29M increase.
  • HighVista Strategies's biggest Q4 2022 reduction was Repare Therapeutics, cutting an estimated $2.08M.
  • HighVista Strategies fully exited Change Healthcare Inc. Common Stock in Q4 2022, selling an estimated $4.46M.
  • HighVista Strategies's ten largest holdings make up 41% of its $168M portfolio in Q4 2022.
  • HighVista Strategies opened 26 new positions and closed 34 in Q4 2022.
  • HighVista Strategies's portfolio value fell 3.8% quarter-over-quarter to $168M.

Based on HighVista Strategies's 13F filing for Q4 2022, filed 14 Feb 2023.