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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+14.9%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$272M
AUM Growth
+$12.6M
Cap. Flow
-$13.6M
Cap. Flow %
-4.98%
Top 10 Hldgs %
27.33%
Holding
177
New
29
Increased
50
Reduced
55
Closed
31

Top Buys

Rank Stock Value
1
VRDN icon
Viridian Therapeutics
VRDN
+$4.13M
2
MLYS icon
Mineralys Therapeutics
MLYS
+$2.18M
3
CLDX icon
Celldex Therapeutics
CLDX
+$2.07M
4
CLF icon
Cleveland-Cliffs
CLF
+$1.9M
5
FERG icon
Ferguson
FERG
+$1.82M

Top Sells

Rank Stock Value
1
ACI icon
Albertsons Companies
ACI
+$4.15M
2
SWTX
SpringWorks Therapeutics
SWTX
+$3.03M
3
GEV icon
GE Vernova
GEV
+$2.41M
4
GOOG icon
Alphabet (Google) Class C
GOOG
+$2.1M
5
BHC icon
Bausch Health
BHC
+$2.03M

Sector Composition

Rank Sector Weight
1 Healthcare 37.62%
2 Technology 22.09%
3 Industrials 8.52%
4 Financials 6.08%
5 Consumer Discretionary 5.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
U icon
76
Unity
U
$19B
$1.38M 0.51%
+57,100
New +$1.26M
NU icon
77
Nu Holdings
NU
$66.7B
$1.38M 0.51%
100,537
+800
+0.8% +$9.58K
BBD icon
78
Banco Bradesco
BBD
$36.1B
$1.37M 0.5%
443,600
-73,400
-14% -$193K
ARGX icon
79
argenx
ARGX
$54.3B
$1.33M 0.49%
2,415
-790
-25% -$458K
CPNG icon
80
Coupang
CPNG
$29.5B
$1.29M 0.47%
43,000
-4,500
-9% -$115K
REXR icon
81
Rexford Industrial Realty
REXR
$8.15B
$1.29M 0.47%
+36,200
New +$1.26M
APG icon
82
APi Group
APG
$18.7B
$1.28M 0.47%
+37,725
New +$1.08M
ETR icon
83
Entergy
ETR
$49.4B
$1.27M 0.47%
+15,300
New +$1.26M
AGX icon
84
Argan
AGX
$8.36B
$1.26M 0.46%
5,700
-6,000
-51% -$1.08M
CAAP icon
85
Corporacion America
CAAP
$4.1B
$1.26M 0.46%
62,000
+1,800
+3% +$35.4K
CNX icon
86
CNX Resources
CNX
$5.3B
$1.25M 0.46%
37,100
-9,600
-21% -$302K
PFSI icon
87
PennyMac Financial
PFSI
$3.96B
$1.25M 0.46%
12,537
-900
-7% -$87.2K
BVN icon
88
Compañía de Minas Buenaventura
BVN
$8.83B
$1.25M 0.46%
75,831
-4,800
-6% -$72.8K
ADBE icon
89
Adobe
ADBE
$107B
$1.24M 0.45%
+3,200
New +$1.23M
PM icon
90
Philip Morris
PM
$289B
$1.22M 0.45%
6,700
-5,400
-45% -$927K
RXO icon
91
RXO
RXO
$3.54B
$1.21M 0.45%
77,100
+8,700
+13% +$132K
PBR.A icon
92
Petrobras Class A
PBR.A
$105B
$1.21M 0.45%
105,000
+16,000
+18% +$178K
MAGN
93
Magnera Corp
MAGN
$468M
$1.2M 0.44%
99,700
+33,100
+50% +$455K
DVAX
94
DELISTED
Dynavax Technologies
DVAX
$1.19M 0.44%
120,271
-114,901
-49% -$1.21M
HCA icon
95
HCA Healthcare
HCA
$90.1B
$1.19M 0.44%
+3,100
New +$1.12M
OFIX icon
96
Orthofix Medical
OFIX
$419M
$1.19M 0.44%
106,500
+13,600
+15% +$169K
OLMA icon
97
Olema Pharmaceuticals
OLMA
$938M
$1.19M 0.44%
278,430
+66,245
+31% +$295K
INSM icon
98
Insmed
INSM
$28.9B
$1.17M 0.43%
11,595
-9,845
-46% -$753K
KGS icon
99
Kodiak Gas Services
KGS
$6.33B
$1.17M 0.43%
+34,000
New +$1.18M
RNAM
100
DELISTED
Avidity Biosciences
RNAM
$1.16M 0.43%
40,864
-13,326
-25% -$397K
2 3
4
5 6

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HighVista Strategies's Q2 2025 Portfolio in Review

As of Q2 2025, HighVista Strategies held 177 positions worth $272M, up 4.9% from $260M the previous quarter. Its ten largest holdings account for 27% of the portfolio.

HighVista Strategies withdrew a net $13.6M in Q2 2025, closing 31 positions and reducing 55 holdings. Its most notable exit was Albertsons Companies, an estimated $4.15M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 38% of assets, down from 39% a quarter earlier, followed by Technology and Industrials.

Against the trend, HighVista Strategies opened a new position in Mineralys Therapeutics worth $2.03M.

  • HighVista Strategies's largest Q2 2025 buy was Mineralys Therapeutics: 150,138 shares worth $2.03M.
  • HighVista Strategies added most to Viridian Therapeutics in Q2 2025, an estimated $4.13M increase.
  • HighVista Strategies's biggest Q2 2025 reduction was GE Vernova, cutting an estimated $2.41M.
  • HighVista Strategies fully exited Albertsons Companies in Q2 2025, selling an estimated $4.15M.
  • HighVista Strategies's ten largest holdings make up 27% of its $272M portfolio in Q2 2025.
  • HighVista Strategies opened 29 new positions and closed 31 in Q2 2025.
  • HighVista Strategies's portfolio value rose 4.9% quarter-over-quarter to $272M.

Based on HighVista Strategies's 13F filing for Q2 2025, filed 14 Aug 2025.