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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+69.32%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$408M
AUM Growth
+$136M
Cap. Flow
+$68.1M
Cap. Flow %
16.68%
Top 10 Hldgs %
29.1%
Holding
175
New
29
Increased
78
Reduced
38
Closed
27

Top Buys

Rank Stock Value
1
ABVX
Abivax
ABVX
+$8.17M
2
AGIO icon
Agios Pharmaceuticals
AGIO
+$4.71M
3
INSM icon
Insmed
INSM
+$4.7M
4
CDTX
Cidara Therapeutics
CDTX
+$4.52M
5
ACLX
Arcellx
ACLX
+$4.35M

Top Sells

Rank Stock Value
1
ANSS
Ansys
ANSS
+$6.01M
2
JNPR
Juniper Networks
JNPR
+$4.58M
3
HES
Hess
HES
+$4M
4
AMED
Amedisys
AMED
+$3.86M
5
WDC icon
Western Digital
WDC
+$2.97M

Sector Composition

Rank Sector Weight
1 Healthcare 59%
2 Technology 12.01%
3 Industrials 6.97%
4 Financials 4.64%
5 Consumer Discretionary 3.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GOOG icon
51
Alphabet (Google) Class C
GOOG
$4.19T
$2.39M 0.59%
+9,800
New +$2.06M
CRH icon
52
CRH
CRH
$67.4B
$2.33M 0.57%
+19,439
New +$2.05M
SRRK icon
53
Scholar Rock
SRRK
$6.34B
$2.22M 0.54%
59,573
+28,343
+91% +$991K
FERG icon
54
Ferguson
FERG
$48.8B
$2.17M 0.53%
9,678
-200
-2% -$45.3K
TLN
55
Talen Energy Corp
TLN
$17.1B
$2.17M 0.53%
5,100
-800
-14% -$289K
PWR icon
56
Quanta Services
PWR
$101B
$2.15M 0.53%
5,200
-1,200
-19% -$466K
AVTR icon
57
Avantor
AVTR
$9.31B
$2.15M 0.53%
+172,400
New +$2.22M
DNTH icon
58
Dianthus Therapeutics
DNTH
$6.07B
$2.13M 0.52%
54,225
+38,364
+242% +$980K
CLH icon
59
Clean Harbors
CLH
$16.4B
$2.11M 0.52%
+9,106
New +$2.16M
LITE icon
60
Lumentum
LITE
$63.8B
$2.1M 0.52%
+12,927
New +$1.61M
FLS icon
61
Flowserve
FLS
$10.3B
$2.07M 0.51%
+38,975
New +$2.12M
COF icon
62
Capital One
COF
$134B
$2.06M 0.5%
+9,674
New +$2.12M
BVN icon
63
Compañía de Minas Buenaventura
BVN
$8.84B
$2.02M 0.49%
82,931
+7,100
+9% +$133K
WDAY icon
64
Workday
WDAY
$44.8B
$1.97M 0.48%
8,191
+2,091
+34% +$483K
PTC icon
65
PTC
PTC
$16.3B
$1.93M 0.47%
9,522
-600
-6% -$122K
AGX icon
66
Argan
AGX
$8.11B
$1.92M 0.47%
7,100
+1,400
+25% +$321K
DVAX
67
DELISTED
Dynavax Technologies
DVAX
$1.91M 0.47%
192,849
+72,578
+60% +$755K
APH icon
68
Amphenol
APH
$206B
$1.91M 0.47%
15,400
-3,600
-19% -$395K
FN icon
69
Fabrinet
FN
$18.8B
$1.86M 0.46%
+5,100
New +$1.68M
BBD icon
70
Banco Bradesco
BBD
$35B
$1.76M 0.43%
520,100
+76,500
+17% +$231K
NU icon
71
Nu Holdings
NU
$65.9B
$1.75M 0.43%
109,337
+8,800
+9% +$123K
QXO
72
QXO Inc
QXO
$16.8B
$1.72M 0.42%
90,200
+5,700
+7% +$118K
WDC icon
73
Western Digital
WDC
$151B
$1.71M 0.42%
14,242
-36,358
-72% -$2.97M
P
74
Everpure Inc
P
$36.4B
$1.71M 0.42%
+20,400
New +$1.36M
KBR icon
75
KBR
KBR
$4.74B
$1.68M 0.41%
+35,500
New +$1.72M
1 2
3
4 5

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HighVista Strategies's Q3 2025 Portfolio in Review

As of Q3 2025, HighVista Strategies held 175 positions worth $408M, up 50% from $272M the previous quarter. Its ten largest holdings account for 29% of the portfolio.

HighVista Strategies deployed $68.1M of net new capital in Q3 2025, opening 29 new positions and adding to 78 existing holdings. Its largest new stake was Cidara Therapeutics: 70,904 shares worth $6.79M.

By sector, the portfolio is most concentrated in Healthcare at 59% of assets, up from 38% a quarter earlier, followed by Technology and Industrials.

On the sell side, the largest reduction was Western Digital, an estimated $2.97M trimmed.

  • HighVista Strategies's largest Q3 2025 buy was Cidara Therapeutics: 70,904 shares worth $6.79M.
  • HighVista Strategies added most to Abivax in Q3 2025, an estimated $8.17M increase.
  • HighVista Strategies's biggest Q3 2025 reduction was Western Digital, cutting an estimated $2.97M.
  • HighVista Strategies fully exited Ansys in Q3 2025, selling an estimated $6.01M.
  • HighVista Strategies's ten largest holdings make up 29% of its $408M portfolio in Q3 2025.
  • HighVista Strategies opened 29 new positions and closed 27 in Q3 2025.
  • HighVista Strategies's portfolio value rose 50% quarter-over-quarter to $408M.

Based on HighVista Strategies's 13F filing for Q3 2025, filed 14 Nov 2025.