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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
-4.54%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$260M
AUM Growth
-$9.28M
Cap. Flow
+$13.5M
Cap. Flow %
5.19%
Top 10 Hldgs %
25.84%
Holding
172
New
35
Increased
39
Reduced
27
Closed
24

Top Buys

Rank Stock Value
1
PWR icon
Quanta Services
PWR
+$2.34M
2
MTZ icon
MasTec
MTZ
+$2.2M
3
MA icon
Mastercard
MA
+$2.01M
4
IMVT icon
Immunovant
IMVT
+$2M
5
MMM icon
3M
MMM
+$1.98M

Top Sells

Rank Stock Value
1
HCP
HashiCorp, Inc. Class A Common Stock
HCP
+$4.45M
2
AMZN icon
Amazon
AMZN
+$3.36M
3
TEVA icon
Teva Pharmaceuticals
TEVA
+$2.23M
4
LYV icon
Live Nation Entertainment
LYV
+$2.02M
5
GH icon
Guardant Health
GH
+$1.83M

Sector Composition

Rank Sector Weight
1 Healthcare 39.15%
2 Technology 17.75%
3 Industrials 8.61%
4 Consumer Discretionary 6.17%
5 Financials 5%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CYTK icon
51
Cytokinetics
CYTK
$10.6B
$1.8M 0.69%
44,749
+30,488
+214% +$1.4M
MLTX icon
52
MoonLake Immunotherapeutics
MLTX
$1.47B
$1.7M 0.66%
43,541
– –
COGT icon
53
Cogent Biosciences
COGT
$6.64B
$1.68M 0.65%
279,673
– –
KNSA icon
54
Kiniksa Pharmaceuticals
KNSA
$6.17B
$1.66M 0.64%
74,639
– –
BKNG icon
55
Booking.com
BKNG
$157B
$1.64M 0.63%
8,925
-7,500
-46% -$1.43M
INSM icon
56
Insmed
INSM
$29.3B
$1.64M 0.63%
21,440
-6,172
-22% -$472K
IMVT icon
57
Immunovant
IMVT
$8.71B
$1.63M 0.63%
+95,648
New +$2M
NATL icon
58
NCR Atleos
NATL
$3.46B
$1.63M 0.63%
+61,900
New +$1.84M
APGE icon
59
Apogee Therapeutics
APGE
$10.2B
$1.61M 0.62%
43,190
– –
BBIO icon
60
BridgeBio Pharma
BBIO
$16.4B
$1.61M 0.62%
46,500
– –
RNAM
61
DELISTED
Avidity Biosciences
RNAM
$1.6M 0.62%
54,190
– –
NVDA icon
62
NVIDIA
NVDA
$5.44T
$1.58M 0.61%
14,600
+3,700
+34% +$469K
PTC icon
63
PTC
PTC
$16B
$1.56M 0.6%
10,081
+1,300
+15% +$224K
LKQ icon
64
LKQ Corp
LKQ
$6.15B
$1.56M 0.6%
+36,700
New +$1.46M
TLN
65
Talen Energy Corp
TLN
$17.5B
$1.54M 0.59%
7,700
+1,000
+15% +$217K
SYRE icon
66
Spyre Therapeutics
SYRE
$9.17B
$1.54M 0.59%
95,159
– –
AGX icon
67
Argan
AGX
$8.22B
$1.53M 0.59%
+11,700
New +$1.63M
OFIX icon
68
Orthofix Medical
OFIX
$415M
$1.52M 0.58%
92,900
+18,900
+26% +$332K
APH icon
69
Amphenol
APH
$211B
$1.5M 0.58%
+22,900
New +$1.56M
PRAX icon
70
Praxis Precision Medicines
PRAX
$10.6B
$1.49M 0.57%
39,286
+28,335
+259% +$1.77M
TSM icon
71
TSMC
TSM
$2.23T
$1.48M 0.57%
8,900
-2,200
-20% -$428K
CNX icon
72
CNX Resources
CNX
$5.26B
$1.47M 0.57%
+46,700
New +$1.41M
CRH icon
73
CRH
CRH
$65.7B
$1.47M 0.57%
+16,700
New +$1.64M
CIEN icon
74
Ciena
CIEN
$61.6B
$1.47M 0.57%
24,300
+5,900
+32% +$466K
CORZ icon
75
Core Scientific
CORZ
$6.62B
$1.44M 0.56%
199,100
+117,800
+145% +$1.34M
1 2
3
4 5

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HighVista Strategies's Q1 2025 Portfolio in Review

As of Q1 2025, HighVista Strategies held 172 positions worth $260M, down 3.5% from $269M the previous quarter. Its ten largest holdings account for 26% of the portfolio.

HighVista Strategies deployed $13.5M of net new capital in Q1 2025, opening 35 new positions and adding to 39 existing holdings. Its largest new stake was Quanta Services: 8,100 shares worth $2.06M.

By sector, the portfolio is most concentrated in Healthcare at 39% of assets, down from 44% a quarter earlier, followed by Technology and Industrials.

On the sell side, the largest reduction was Amazon, an estimated $3.36M trimmed.

  • HighVista Strategies's largest Q1 2025 buy was Quanta Services: 8,100 shares worth $2.06M.
  • HighVista Strategies added most to Praxis Precision Medicines in Q1 2025, an estimated $1.77M increase.
  • HighVista Strategies's biggest Q1 2025 reduction was Amazon, cutting an estimated $3.36M.
  • HighVista Strategies fully exited HashiCorp, Inc. Class A Common Stock in Q1 2025, selling an estimated $4.45M.
  • HighVista Strategies's ten largest holdings make up 26% of its $260M portfolio in Q1 2025.
  • HighVista Strategies opened 35 new positions and closed 24 in Q1 2025.
  • HighVista Strategies's portfolio value fell 3.5% quarter-over-quarter to $260M.

Based on HighVista Strategies's 13F filing for Q1 2025, filed 15 May 2025.