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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+16.91%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$276M
AUM Growth
+$59.5M
Cap. Flow
+$34.9M
Cap. Flow %
12.66%
Top 10 Hldgs %
29.49%
Holding
157
New
25
Increased
65
Reduced
12
Closed
31

Top Buys

Rank Stock Value
1
SYRE icon
Spyre Therapeutics
SYRE
+$7.96M
2
HES
Hess
HES
+$4.24M
3
SOVO
Sovos Brands, Inc. Common Stock
SOVO
+$4.06M
4
SP
SP Plus Corporation
SP
+$3.96M
5
PATH icon
UiPath
PATH
+$2.41M

Top Sells

Rank Stock Value
1
ATVI
Activision Blizzard
ATVI
+$5.76M
2
VMW
VMware, Inc
VMW
+$5.59M
3
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
+$4.04M
4
SGEN
Seagen Inc. Common Stock
SGEN
+$4.03M
5
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
+$1.53M

Sector Composition

Rank Sector Weight
1 Healthcare 45.71%
2 Technology 11.75%
3 Consumer Discretionary 6.51%
4 Industrials 5.31%
5 Consumer Staples 4.66%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BBIO icon
51
BridgeBio Pharma
BBIO
$16.5B
$1.8M 0.65%
44,572
– –
SGI
52
Somnigroup International
SGI
$13.9B
$1.73M 0.63%
34,000
+14,100
+71% +$598K
CHTR icon
53
Charter Communications
CHTR
$18.6B
$1.72M 0.63%
4,434
+2,800
+171% +$1.14M
X
54
DELISTED
US Steel
X
$1.72M 0.63%
35,400
-7,500
-17% -$273K
LAD icon
55
Lithia Motors
LAD
$8.35B
$1.71M 0.62%
5,201
+1,500
+41% +$412K
RTX icon
56
RTX Corp
RTX
$302B
$1.7M 0.62%
20,200
+12,100
+149% +$958K
MRC
57
DELISTED
MRC Global
MRC
$1.67M 0.61%
+151,800
New +$1.59M
COGT icon
58
Cogent Biosciences
COGT
$6.66B
$1.65M 0.6%
281,093
+82,506
+42% +$632K
FCNCA icon
59
First Citizens BancShares
FCNCA
$25.2B
$1.65M 0.6%
1,161
+200
+21% +$281K
PTC icon
60
PTC
PTC
$16.3B
$1.64M 0.6%
9,381
+2,300
+32% +$353K
PFSI icon
61
PennyMac Financial
PFSI
$3.94B
$1.59M 0.58%
17,937
+1,700
+10% +$128K
KNSA icon
62
Kiniksa Pharmaceuticals
KNSA
$6.07B
$1.56M 0.56%
+88,688
New +$1.46M
MU icon
63
Micron Technology
MU
$962B
$1.51M 0.55%
17,700
-10,500
-37% -$780K
TECK icon
64
Teck Resources
TECK
$32.5B
$1.46M 0.53%
34,562
+14,600
+73% +$561K
JD icon
65
JD.com
JD
$43.1B
$1.45M 0.53%
50,265
+15,700
+45% +$425K
SLB icon
66
SLB Ltd
SLB
$79.1B
$1.39M 0.5%
26,700
+8,300
+45% +$451K
WDC icon
67
Western Digital
WDC
$151B
$1.37M 0.5%
34,530
+7,938
+30% +$278K
STX icon
68
Seagate
STX
$185B
$1.35M 0.49%
+15,800
New +$1.18M
LLY icon
69
Eli Lilly
LLY
$1.09T
$1.34M 0.49%
2,300
+900
+64% +$525K
TRU icon
70
TransUnion
TRU
$15.4B
$1.33M 0.48%
19,400
+11,800
+155% +$719K
ELV icon
71
Elevance Health
ELV
$84.8B
$1.32M 0.48%
2,795
+1,395
+100% +$645K
ROP icon
72
Roper Technologies
ROP
$39.7B
$1.32M 0.48%
2,413
+1,000
+71% +$515K
TEVA icon
73
Teva Pharmaceuticals
TEVA
$42.5B
$1.3M 0.47%
124,700
+400
+0.3% +$3.73K
HUBS icon
74
HubSpot
HUBS
$10.9B
$1.28M 0.46%
+2,200
New +$1.06M
PODD icon
75
Insulet
PODD
$9.91B
$1.24M 0.45%
+5,700
New +$978K
1 2
3
4 5

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HighVista Strategies's Q4 2023 Portfolio in Review

As of Q4 2023, HighVista Strategies held 157 positions worth $276M, up 28% from $216M the previous quarter. Its ten largest holdings account for 29% of the portfolio.

HighVista Strategies deployed $34.9M of net new capital in Q4 2023, opening 25 new positions and adding to 65 existing holdings. Its largest new stake was Spyre Therapeutics: 577,616 shares worth $12.4M.

By sector, the portfolio is most concentrated in Healthcare at 46% of assets, down from 46% a quarter earlier, followed by Technology and Consumer Discretionary.

On the sell side, the largest reduction was Micron Technology, an estimated $780K trimmed.

  • HighVista Strategies's largest Q4 2023 buy was Spyre Therapeutics: 577,616 shares worth $12.4M.
  • HighVista Strategies added most to Cerevel Therapeutics Holdings, Inc. Common Stock in Q4 2023, an estimated $2.08M increase.
  • HighVista Strategies's biggest Q4 2023 reduction was Micron Technology, cutting an estimated $780K.
  • HighVista Strategies fully exited Activision Blizzard in Q4 2023, selling an estimated $5.76M.
  • HighVista Strategies's ten largest holdings make up 29% of its $276M portfolio in Q4 2023.
  • HighVista Strategies opened 25 new positions and closed 31 in Q4 2023.
  • HighVista Strategies's portfolio value rose 28% quarter-over-quarter to $276M.

Based on HighVista Strategies's 13F filing for Q4 2023, filed 14 Feb 2024.