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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
-6.86%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$166M
AUM Growth
+$8.35M
Cap. Flow
+$27.8M
Cap. Flow %
16.81%
Top 10 Hldgs %
40.91%
Holding
125
New
39
Increased
43
Reduced
18
Closed
15

Sector Composition

Rank Sector Weight
1 Healthcare 46.47%
2 Technology 22.39%
3 Financials 16.85%
4 Communication Services 4.29%
5 Consumer Discretionary 2.94%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MRTX
51
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$745K 0.45%
11,096
+1,343
+14% +$85.4K
ARQT icon
52
Arcutis Biotherapeutics
ARQT
$3.26B
$734K 0.44%
+34,462
New +$707K
ALNY icon
53
Alnylam Pharmaceuticals
ALNY
$29B
$728K 0.44%
4,988
-567
-10% -$80.4K
SRPT icon
54
Sarepta Therapeutics
SRPT
$1.81B
$718K 0.43%
9,581
-1,729
-15% -$127K
BMRN icon
55
BioMarin Pharmaceuticals
BMRN
$13.3B
$712K 0.43%
8,596
+3,003
+54% +$239K
ASND icon
56
Ascendis Pharma A/S
ASND
$16.8B
$692K 0.42%
7,442
-379
-5% -$35.7K
XENE icon
57
Xenon Pharmaceuticals
XENE
$6.21B
$682K 0.41%
22,435
-5,557
-20% -$168K
ANAB icon
58
AnaptysBio
ANAB
$1.64B
$672K 0.41%
33,103
+19,105
+136% +$423K
TCDA
59
DELISTED
Tricida, Inc. Common Stock
TCDA
$664K 0.4%
68,548
-38,654
-36% -$368K
ARVN icon
60
Arvinas
ARVN
$588M
$660K 0.4%
+15,686
New +$787K
LKFT
61
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.76B
$658K 0.4%
11,801
-1,408
-11% -$83.5K
GOOG icon
62
Alphabet (Google) Class C
GOOG
$4.35T
$647K 0.39%
+5,920
New +$699K
GHRS icon
63
GH Research
GHRS
$2.03B
$638K 0.39%
63,936
+11,096
+21% +$144K
MORF
64
DELISTED
Morphic Holding, Inc. Common Stock
MORF
$634K 0.38%
29,230
+18,313
+168% +$511K
NTRA icon
65
Natera
NTRA
$45.9B
$631K 0.38%
17,812
+4,364
+32% +$162K
CRNX icon
66
Crinetics Pharmaceuticals
CRNX
$8.93B
$614K 0.37%
32,948
-11,278
-26% -$225K
BPMC
67
DELISTED
Blueprint Medicines
BPMC
$612K 0.37%
+12,108
New +$709K
PCVX icon
68
Vaxcyte
PCVX
$8.67B
$609K 0.37%
+27,965
New +$647K
CLDX icon
69
Celldex Therapeutics
CLDX
$3.37B
$604K 0.36%
22,412
-3,326
-13% -$96.6K
HZNP
70
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$592K 0.36%
7,419
-837
-10% -$79.3K
ACAD icon
71
Acadia Pharmaceuticals
ACAD
$5.06B
$562K 0.34%
39,900
+5,784
+17% +$108K
RLMD icon
72
Relmada Therapeutics
RLMD
$484M
$560K 0.34%
29,493
+8,112
+38% +$177K
ISEE
73
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$557K 0.34%
57,919
+4,336
+8% +$54.4K
AMZN icon
74
Amazon
AMZN
$3T
$538K 0.32%
+5,068
New +$634K
VRDN icon
75
Viridian Therapeutics
VRDN
$2.61B
$521K 0.31%
45,039
-4,026
-8% -$54.1K

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HighVista Strategies's Q2 2022 Portfolio in Review

As of Q2 2022, HighVista Strategies held 125 positions worth $166M, up 5.3% from $157M the previous quarter. Its ten largest holdings account for 41% of the portfolio.

HighVista Strategies deployed $27.8M of net new capital in Q2 2022, opening 39 new positions and adding to 43 existing holdings. Its largest new stake was iShares Russell 1000 Value ETF: 23,825 shares worth $3.45M.

By sector, the portfolio is most concentrated in Healthcare at 46% of assets, up from 44% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was Protagonist Therapeutics, an estimated $551K trimmed.

  • HighVista Strategies's largest Q2 2022 buy was iShares Russell 1000 Value ETF: 23,825 shares worth $3.45M.
  • HighVista Strategies added most to Mastercard in Q2 2022, an estimated $4.42M increase.
  • HighVista Strategies's biggest Q2 2022 reduction was Protagonist Therapeutics, cutting an estimated $551K.
  • HighVista Strategies fully exited People's United Financial Inc in Q2 2022, selling an estimated $3.92M.
  • HighVista Strategies's ten largest holdings make up 41% of its $166M portfolio in Q2 2022.
  • HighVista Strategies opened 39 new positions and closed 15 in Q2 2022.
  • HighVista Strategies's portfolio value rose 5.3% quarter-over-quarter to $166M.

Based on HighVista Strategies's 13F filing for Q2 2022, filed 15 Aug 2022.