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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+16.45%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$157M
AUM Growth
+$19.3M
Cap. Flow
+$6.96M
Cap. Flow %
4.45%
Top 10 Hldgs %
59.23%
Holding
147
New
34
Increased
35
Reduced
16
Closed
30

Sector Composition

Rank Sector Weight
1 Technology 36.93%
2 Healthcare 27.25%
3 Financials 7.02%
4 Consumer Discretionary 4.71%
5 Communication Services 4.34%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
AVDL
51
DELISTED
Avadel Pharmaceuticals
AVDL
$744K 0.48%
111,431
+53,936
+94% +$337K
RLMD icon
52
Relmada Therapeutics
RLMD
$477M
$720K 0.46%
22,450
+9,885
+79% +$340K
AKRO
53
DELISTED
Akero Therapeutics
AKRO
$716K 0.46%
+27,739
New +$772K
ZYME icon
54
Zymeworks
ZYME
$1.73B
$690K 0.44%
14,608
-1,702
-10% -$79K
GERN icon
55
Geron
GERN
$1.05B
$681K 0.43%
428,069
+150,989
+54% +$275K
RNAM
56
DELISTED
Avidity Biosciences
RNAM
$680K 0.43%
26,665
+9,463
+55% +$276K
CBAY
57
DELISTED
Cymabay Therapeutics
CBAY
$669K 0.43%
+116,519
New +$882K
DCPH
58
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$658K 0.42%
11,534
+951
+9% +$56.4K
NVTA
59
DELISTED
Invitae Corporation
NVTA
$644K 0.41%
15,413
NVAX icon
60
Novavax
NVAX
$1.31B
$638K 0.41%
+5,722
New +$608K
FMTX
61
DELISTED
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$637K 0.41%
18,252
+5,927
+48% +$258K
DBC icon
62
Invesco DB Commodity Index Tracking Fund
DBC
$1.72B
$623K 0.4%
42,396
RLAY icon
63
Relay Therapeutics
RLAY
$4.38B
$622K 0.4%
+14,975
New +$677K
ITOS
64
DELISTED
iTeos Therapeutics
ITOS
$605K 0.39%
+17,880
New +$473K
ADVM
65
DELISTED
Adverum Biotechnologies
ADVM
$591K 0.38%
5,453
+1,873
+52% +$232K
NVO
66
Novo Nordisk
NVO
$207B
$537K 0.34%
15,390
+1,190
+8% +$41.1K
DYN icon
67
Dyne Therapeutics
DYN
$4.99B
$499K 0.32%
+23,760
New +$470K
BCEL
68
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$498K 0.32%
+30,824
New +$462K
CHKP icon
69
Check Point Software Technologies
CHKP
$13.2B
$343K 0.22%
2,584
+584
+29% +$71.4K
MBT
70
DELISTED
Mobile TeleSystems Public Joint Stock Company American Depositary Shares (Each representing 2 Shares
MBT
$289K 0.18%
32,259
-27,941
-46% -$237K
SCCO icon
71
Southern Copper
SCCO
$164B
$247K 0.16%
+4,148
New +$211K
VRNA
72
DELISTED
Verona Pharma
VRNA
$187K 0.12%
+26,681
New +$180K
BCRX icon
73
BioCryst Pharmaceuticals
BCRX
$2.64B
$185K 0.12%
24,800
UBS icon
74
UBS Group
UBS
$176B
$162K 0.1%
12,991
-2,089
-14% -$27.7K
TPCO
75
DELISTED
Tribune Publishing Company Common Stock
TPCO
$153K 0.1%
11,200

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HighVista Strategies's Q4 2020 Portfolio in Review

As of Q4 2020, HighVista Strategies held 147 positions worth $157M, up 14% from $137M the previous quarter. Its ten largest holdings account for 59% of the portfolio.

HighVista Strategies deployed $6.96M of net new capital in Q4 2020, opening 34 new positions and adding to 35 existing holdings. Its largest new stake was DouYu International Holdings: 24,960 shares worth $2.76M.

By sector, the portfolio is most concentrated in Technology at 37% of assets, up from 37% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Alibaba, an estimated $1.25M trimmed.

  • HighVista Strategies's largest Q4 2020 buy was DouYu International Holdings: 24,960 shares worth $2.76M.
  • HighVista Strategies added most to Adaptimmune Therapeutics in Q4 2020, an estimated $564K increase.
  • HighVista Strategies's biggest Q4 2020 reduction was Alibaba, cutting an estimated $1.25M.
  • HighVista Strategies fully exited TD Ameritrade Holding Corp in Q4 2020, selling an estimated $7.15M.
  • HighVista Strategies's ten largest holdings make up 59% of its $157M portfolio in Q4 2020.
  • HighVista Strategies opened 34 new positions and closed 30 in Q4 2020.
  • HighVista Strategies's portfolio value rose 14% quarter-over-quarter to $157M.

Based on HighVista Strategies's 13F filing for Q4 2020, filed 16 Feb 2021.