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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+16.91%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$276M
AUM Growth
+$59.5M
Cap. Flow
+$34.9M
Cap. Flow %
12.66%
Top 10 Hldgs %
29.49%
Holding
157
New
25
Increased
65
Reduced
12
Closed
31

Top Buys

Rank Stock Value
1
SYRE icon
Spyre Therapeutics
SYRE
+$7.96M
2
HES
Hess
HES
+$4.24M
3
SOVO
Sovos Brands, Inc. Common Stock
SOVO
+$4.06M
4
SP
SP Plus Corporation
SP
+$3.96M
5
PATH icon
UiPath
PATH
+$2.41M

Top Sells

Rank Stock Value
1
ATVI
Activision Blizzard
ATVI
+$5.76M
2
VMW
VMware, Inc
VMW
+$5.59M
3
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
+$4.04M
4
SGEN
Seagen Inc. Common Stock
SGEN
+$4.03M
5
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
+$1.53M

Sector Composition

Rank Sector Weight
1 Healthcare 45.71%
2 Technology 11.75%
3 Consumer Discretionary 6.51%
4 Industrials 5.31%
5 Consumer Staples 4.66%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PATH icon
26
UiPath
PATH
$8.08B
$3.07M 1.11%
+123,675
New +$2.41M
GPCR icon
27
Structure Therapeutics
GPCR
$3.82B
$3.05M 1.11%
74,832
– –
TXNM
28
TXNM Energy Inc
TXNM
$5.91B
$2.91M 1.06%
69,909
– –
IONS icon
29
Ionis Pharmaceuticals
IONS
$9.46B
$2.9M 1.05%
57,348
+8,828
+18% +$423K
AMAM
30
DELISTED
Ambrx Biopharma Inc
AMAM
$2.89M 1.05%
203,122
+9,421
+5% +$107K
BCYC
31
Bicycle Therapeutics
BCYC
$288M
$2.86M 1.04%
158,293
+65,859
+71% +$1.09M
IMCR icon
32
Immunocore
IMCR
$1.73B
$2.84M 1.03%
41,627
+1,823
+5% +$94.8K
LEGN icon
33
Legend Biotech
LEGN
$4B
$2.67M 0.97%
44,305
– –
MA icon
34
Mastercard
MA
$493B
$2.58M 0.94%
6,047
+2,300
+61% +$924K
INDV icon
35
Indivior Pharmaceuticals
INDV
$4.54B
$2.49M 0.9%
164,841
+34,841
+27% +$619K
META icon
36
Meta Platforms (Facebook)
META
$1.52T
$2.44M 0.89%
6,890
+2,700
+64% +$879K
XENE icon
37
Xenon Pharmaceuticals
XENE
$6.21B
$2.39M 0.87%
51,801
+16,546
+47% +$585K
BKNG icon
38
Booking.com
BKNG
$160B
$2.33M 0.85%
16,425
+7,500
+84% +$935K
XPO icon
39
XPO
XPO
$23.5B
$2.28M 0.83%
25,980
-200
-0.8% -$16.3K
XOMA
40
DELISTED
Xoma
XOMA
$2.2M 0.8%
118,899
– –
DVAX
41
DELISTED
Dynavax Technologies
DVAX
$2.18M 0.79%
156,161
+23,161
+17% +$322K
GE icon
42
GE Aerospace
GE
$380B
$2.17M 0.79%
21,327
+8,896
+72% +$824K
WCC
43
WESCO International
WCC
$17.9B
$2.1M 0.76%
12,097
+5,200
+75% +$779K
FISV
44
Fiserv Inc
FISV
$27.8B
$1.99M 0.72%
14,953
+4,000
+37% +$491K
INTU icon
45
Intuit
INTU
$91.5B
$1.98M 0.72%
3,163
+1,000
+46% +$552K
TVTX icon
46
Travere Therapeutics
TVTX
$5.74B
$1.97M 0.72%
219,416
+97,016
+79% +$706K
LAUR icon
47
Laureate Education
LAUR
$5.13B
$1.95M 0.71%
142,507
+74,600
+110% +$1.02M
ELVN icon
48
Enliven Therapeutics
ELVN
$4.35B
$1.9M 0.69%
137,241
+12,654
+10% +$155K
IMRX icon
49
Immuneering
IMRX
$293M
$1.87M 0.68%
254,513
– –
GOOG icon
50
Alphabet (Google) Class C
GOOG
$4.35T
$1.85M 0.67%
13,136
-3,500
-21% -$475K
1
2
3 4 5

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HighVista Strategies's Q4 2023 Portfolio in Review

As of Q4 2023, HighVista Strategies held 157 positions worth $276M, up 28% from $216M the previous quarter. Its ten largest holdings account for 29% of the portfolio.

HighVista Strategies deployed $34.9M of net new capital in Q4 2023, opening 25 new positions and adding to 65 existing holdings. Its largest new stake was Spyre Therapeutics: 577,616 shares worth $12.4M.

By sector, the portfolio is most concentrated in Healthcare at 46% of assets, down from 46% a quarter earlier, followed by Technology and Consumer Discretionary.

On the sell side, the largest reduction was Micron Technology, an estimated $780K trimmed.

  • HighVista Strategies's largest Q4 2023 buy was Spyre Therapeutics: 577,616 shares worth $12.4M.
  • HighVista Strategies added most to Cerevel Therapeutics Holdings, Inc. Common Stock in Q4 2023, an estimated $2.08M increase.
  • HighVista Strategies's biggest Q4 2023 reduction was Micron Technology, cutting an estimated $780K.
  • HighVista Strategies fully exited Activision Blizzard in Q4 2023, selling an estimated $5.76M.
  • HighVista Strategies's ten largest holdings make up 29% of its $276M portfolio in Q4 2023.
  • HighVista Strategies opened 25 new positions and closed 31 in Q4 2023.
  • HighVista Strategies's portfolio value rose 28% quarter-over-quarter to $276M.

Based on HighVista Strategies's 13F filing for Q4 2023, filed 14 Feb 2024.