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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+3.84%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$135M
AUM Growth
-$22M
Cap. Flow
-$25.1M
Cap. Flow %
-18.68%
Top 10 Hldgs %
55.15%
Holding
156
New
39
Increased
27
Reduced
28
Closed
31

Top Buys

Rank Stock Value
1
MSDAU
MSD Acquisition Corp. Unit
MSDAU
+$5.02M
2
WORK
Slack Technologies, Inc.
WORK
+$3.37M
3
RP
RealPage, Inc.
RP
+$3.36M
4
ALXN
Alexion Pharmaceuticals
ALXN
+$3.33M
5
ATHM icon
Autohome
ATHM
+$1.65M

Top Sells

Rank Stock Value
1
DELL icon
Dell
DELL
+$26.3M
2
TIF
Tiffany & Co.
TIF
+$6.72M
3
ACIA
Acacia Communications Inc
ACIA
+$3.24M
4
FIT
Fitbit, Inc. Class A common stock
FIT
+$3.07M
5
BIDU icon
Baidu
BIDU
+$2.66M

Sector Composition

Rank Sector Weight
1 Technology 31.89%
2 Healthcare 28.92%
3 Financials 8.63%
4 Consumer Discretionary 6.74%
5 Communication Services 4.35%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AVDL
26
DELISTED
Avadel Pharmaceuticals
AVDL
$841K 0.62%
93,059
-18,372
-16% -$149K
CRIS icon
27
Curis
CRIS
$7.13M
$835K 0.62%
+184
New +$770K
HZNP
28
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$790K 0.59%
+8,588
New +$725K
KRON
29
DELISTED
Kronos Bio
KRON
$789K 0.59%
+26,944
New +$789K
RVMD icon
30
Revolution Medicines
RVMD
$44.4B
$780K 0.58%
+16,992
New +$762K
SNDX icon
31
Syndax Pharmaceuticals
SNDX
$1.82B
$779K 0.58%
+34,873
New +$788K
ONC
32
BeOne Medicines Ltd
ONC
$40.6B
$777K 0.58%
+2,231
New +$739K
SAGE
33
DELISTED
Sage Therapeutics
SAGE
$757K 0.56%
10,111
+430
+4% +$35.3K
ARNA
34
DELISTED
Arena Pharmaceuticals Inc
ARNA
$739K 0.55%
10,656
-1,464
-12% -$113K
MRTX
35
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$731K 0.54%
4,266
+703
+20% +$139K
SWTX
36
DELISTED
SpringWorks Therapeutics
SWTX
$711K 0.53%
9,669
-2,743
-22% -$215K
TRIL
37
DELISTED
Trillium Therapeutics Inc.
TRIL
$711K 0.53%
66,243
-1,992
-3% -$24.6K
ASND icon
38
Ascendis Pharma A/S
ASND
$16.8B
$709K 0.53%
5,505
+774
+16% +$118K
DBC icon
39
Invesco DB Commodity Index Tracking Fund
DBC
$1.72B
$704K 0.52%
42,396
– –
RNAM
40
DELISTED
Avidity Biosciences
RNAM
$693K 0.52%
31,797
+5,132
+19% +$126K
PMVP icon
41
PMV Pharmaceuticals
PMVP
$65.6M
$687K 0.51%
20,878
-1,776
-8% -$70K
IGMS
42
DELISTED
IGM Biosciences
IGMS
$684K 0.51%
8,921
-3,033
-25% -$276K
TARS icon
43
Tarsus Pharmaceuticals
TARS
$2.97B
$680K 0.51%
+21,084
New +$780K
CLDX icon
44
Celldex Therapeutics
CLDX
$3.37B
$678K 0.5%
32,940
-16,915
-34% -$388K
ITOS
45
DELISTED
iTeos Therapeutics
ITOS
$677K 0.5%
19,804
+1,924
+11% +$69.5K
ZYME icon
46
Zymeworks
ZYME
$1.71B
$663K 0.49%
21,002
+6,394
+44% +$260K
AXSM icon
47
Axsome Therapeutics
AXSM
$11.4B
$660K 0.49%
11,664
+651
+6% +$45.8K
CCXI
48
DELISTED
ChemoCentryx, Inc.
CCXI
$657K 0.49%
12,817
-1,658
-11% -$99.8K
CCCC icon
49
C4 Therapeutics
CCCC
$400M
$651K 0.48%
+17,587
New +$700K
ARGX icon
50
argenx
ARGX
$54.2B
$649K 0.48%
2,357
-426
-15% -$135K
1
2
3 4 5

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HighVista Strategies's Q1 2021 Portfolio in Review

As of Q1 2021, HighVista Strategies held 156 positions worth $135M, down 14% from $157M the previous quarter. Its ten largest holdings account for 55% of the portfolio.

HighVista Strategies withdrew a net $25.1M in Q1 2021, closing 31 positions and reducing 28 holdings. Its most notable exit was Tiffany & Co., an estimated $6.72M position sold in full.

By sector, the portfolio is most concentrated in Technology at 32% of assets, down from 37% a quarter earlier, followed by Healthcare and Financials.

Against the trend, HighVista Strategies opened a new position in MSD Acquisition Corp. Unit worth $5.08M.

  • HighVista Strategies's largest Q1 2021 buy was MSD Acquisition Corp. Unit: 500,000 shares worth $5.08M.
  • HighVista Strategies added most to Alibaba in Q1 2021, an estimated $700K increase.
  • HighVista Strategies's biggest Q1 2021 reduction was Dell, cutting an estimated $26.3M.
  • HighVista Strategies fully exited Tiffany & Co. in Q1 2021, selling an estimated $6.72M.
  • HighVista Strategies's ten largest holdings make up 55% of its $135M portfolio in Q1 2021.
  • HighVista Strategies opened 39 new positions and closed 31 in Q1 2021.
  • HighVista Strategies's portfolio value fell 14% quarter-over-quarter to $135M.

Based on HighVista Strategies's 13F filing for Q1 2021, filed 17 May 2021.