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HighVista Strategies Portfolio holdings

AUM $362M
1-Year Est. Return 230.96%
This Fund
S&P 500
This Quarter Est. Return
+16.45%
1 Year Est. Return
+230.96%
3 Year Est. Return
+518.4%
5 Year Est. Return
+644.94%
10 Year Est. Return
+2,223.31%
AUM
$157M
AUM Growth
+$19.3M
Cap. Flow
+$6.96M
Cap. Flow %
4.45%
Top 10 Hldgs %
59.23%
Holding
147
New
34
Increased
35
Reduced
16
Closed
30

Sector Composition

Rank Sector Weight
1 Technology 36.93%
2 Healthcare 27.25%
3 Financials 7.02%
4 Consumer Discretionary 4.71%
5 Communication Services 4.34%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
TRIL
26
DELISTED
Trillium Therapeutics Inc.
TRIL
$1M 0.64%
68,235
+15,894
+30% +$229K
CYTK icon
27
Cytokinetics
CYTK
$10.8B
$987K 0.63%
+47,520
New +$868K
NGNE icon
28
Neurogene
NGNE
$704M
$983K 0.63%
3,486
+1,524
+78% +$372K
SRPT icon
29
Sarepta Therapeutics
SRPT
$1.89B
$966K 0.62%
+5,667
New +$840K
TSM icon
30
TSMC
TSM
$2.18T
$955K 0.61%
8,756
-1,244
-12% -$118K
IOVA icon
31
Iovance Biotherapeutics
IOVA
$2.93B
$948K 0.61%
20,423
+3,599
+21% +$143K
ARNA
32
DELISTED
Arena Pharmaceuticals Inc
ARNA
$931K 0.59%
12,120
+4,699
+63% +$352K
FOLD
33
DELISTED
Amicus Therapeutics
FOLD
$918K 0.59%
39,774
+6,881
+21% +$141K
CNST
34
DELISTED
Constellation Pharmaceuticals, Inc.
CNST
$918K 0.59%
31,881
+12,217
+62% +$308K
SWTX
35
DELISTED
SpringWorks Therapeutics
SWTX
$900K 0.57%
12,412
+935
+8% +$60.2K
AXSM icon
36
Axsome Therapeutics
AXSM
$11.2B
$897K 0.57%
11,013
+5,001
+83% +$374K
CCXI
37
DELISTED
ChemoCentryx, Inc.
CCXI
$896K 0.57%
14,475
+5,080
+54% +$291K
CLDX icon
38
Celldex Therapeutics
CLDX
$3.47B
$873K 0.56%
49,855
+5,026
+11% +$90.5K
ADAP
39
DELISTED
Adaptimmune Therapeutics
ADAP
$859K 0.55%
159,351
+103,872
+187% +$564K
SAGE
40
DELISTED
Sage Therapeutics
SAGE
$838K 0.54%
9,681
+499
+5% +$36.8K
IMVT icon
41
Immunovant
IMVT
$8.37B
$827K 0.53%
17,905
ARGX icon
42
argenx
ARGX
$53.9B
$818K 0.52%
2,783
+725
+35% +$199K
ALT icon
43
Altimmune
ALT
$587M
$816K 0.52%
+72,378
New +$853K
ISEE
44
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$809K 0.52%
117,060
+21,085
+22% +$135K
KURA icon
45
Kura Oncology
KURA
$882M
$807K 0.52%
24,708
-125
-0.5% -$4.39K
MGNX icon
46
MacroGenics
MGNX
$253M
$791K 0.51%
34,605
+16,461
+91% +$379K
ASND icon
47
Ascendis Pharma A/S
ASND
$16.7B
$789K 0.5%
4,731
+1,424
+43% +$235K
MRTX
48
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$783K 0.5%
3,563
+163
+5% +$35.2K
ACAD icon
49
Acadia Pharmaceuticals
ACAD
$5.09B
$767K 0.49%
14,344
+1,915
+15% +$95.1K
GBT
50
DELISTED
Global Blood Therapeutics, Inc.
GBT
$753K 0.48%
17,389
+9,840
+130% +$485K

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HighVista Strategies's Q4 2020 Portfolio in Review

As of Q4 2020, HighVista Strategies held 147 positions worth $157M, up 14% from $137M the previous quarter. Its ten largest holdings account for 59% of the portfolio.

HighVista Strategies deployed $6.96M of net new capital in Q4 2020, opening 34 new positions and adding to 35 existing holdings. Its largest new stake was DouYu International Holdings: 24,960 shares worth $2.76M.

By sector, the portfolio is most concentrated in Technology at 37% of assets, up from 37% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Alibaba, an estimated $1.25M trimmed.

  • HighVista Strategies's largest Q4 2020 buy was DouYu International Holdings: 24,960 shares worth $2.76M.
  • HighVista Strategies added most to Adaptimmune Therapeutics in Q4 2020, an estimated $564K increase.
  • HighVista Strategies's biggest Q4 2020 reduction was Alibaba, cutting an estimated $1.25M.
  • HighVista Strategies fully exited TD Ameritrade Holding Corp in Q4 2020, selling an estimated $7.15M.
  • HighVista Strategies's ten largest holdings make up 59% of its $157M portfolio in Q4 2020.
  • HighVista Strategies opened 34 new positions and closed 30 in Q4 2020.
  • HighVista Strategies's portfolio value rose 14% quarter-over-quarter to $157M.

Based on HighVista Strategies's 13F filing for Q4 2020, filed 16 Feb 2021.