FM

Frazier Management Portfolio holdings

AUM $1.12M
This Quarter Return
-4.68%
1 Year Return
+150.24%
3 Year Return
+430.4%
5 Year Return
+1,926.83%
10 Year Return
–
AUM
$1.08B
AUM Growth
+$1.08B
Cap. Flow
-$65.3M
Cap. Flow %
-6.02%
Top 10 Hldgs %
77.96%
Holding
37
New
2
Increased
1
Reduced
8
Closed
3

Top Buys

1
IOVA icon
Iovance Biotherapeutics
IOVA
$21.5M
2
KDNY
Chinook Therapeutics, Inc. Common Stock
KDNY
$15.5M
3
AUTL
Autolus Therapeutics
AUTL
$15.2M

Top Sells

1
ARQT icon
Arcutis Biotherapeutics
ARQT
$57.5M
2
TARS icon
Tarsus Pharmaceuticals
TARS
$14.5M
3
ADVM icon
Adverum Biotechnologies
ADVM
$14.2M
4
KRYS icon
Krystal Biotech
KRYS
$7.28M
5
ACRS icon
Aclaris Therapeutics
ACRS
$5.71M

Sector Composition

1 Healthcare 95.82%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ARQT icon
1
Arcutis Biotherapeutics
ARQT
$1.86B
$230M 21.23% 8,434,232 -2,108,558 -20% -$57.5M
PHAT icon
2
Phathom Pharmaceuticals
PHAT
$864M
$197M 18.19% 5,827,415 – –
PASG icon
3
Passage Bio
PASG
$22.7M
$66.3M 6.12% 5,009,219 – –
MIRM icon
4
Mirum Pharmaceuticals
MIRM
$3.71B
$61.7M 5.69% 3,566,912 – –
TBIO
5
DELISTED
Translate Bio, Inc. Common Stock
TBIO
$57.4M 5.29% 2,082,789 -100,000 -5% -$2.75M
IOVA icon
6
Iovance Biotherapeutics
IOVA
$807M
$55.6M 5.13% 2,137,999 +825,000 +63% +$21.5M
KRYS icon
7
Krystal Biotech
KRYS
$4.27B
$53.6M 4.94% 787,876 -107,124 -12% -$7.28M
PCVX icon
8
Vaxcyte
PCVX
$4B
$52M 4.79% 2,309,554 – –
TARS icon
9
Tarsus Pharmaceuticals
TARS
$2.47B
$41.1M 3.79% 1,417,157 -500,000 -26% -$14.5M
TRIL
10
DELISTED
Trillium Therapeutics Inc.
TRIL
$30.3M 2.79% 3,123,107 – –
ANAB icon
11
AnaptysBio
ANAB
$569M
$23.3M 2.15% 899,700 – –
ALPN
12
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$23.1M 2.13% 2,571,450 – –
SNDX icon
13
Syndax Pharmaceuticals
SNDX
$1.41B
$20.4M 1.88% 1,188,135 -246,910 -17% -$4.24M
STRO icon
14
Sutro Biopharma
STRO
$72.7M
$18.6M 1.72% 1,001,421 – –
ISEE
15
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$16.1M 1.48% 2,544,500 – –
KDNY
16
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$15.5M 1.43% +1,100,000 New +$15.5M
AUTL
17
Autolus Therapeutics
AUTL
$399M
$15.2M 1.4% +2,283,966 New +$15.2M
FLACU
18
DELISTED
Frazier Lifesciences Acquisition Corporation Unit
FLACU
$15.1M 1.39% 1,501,000 – –
RGNX icon
19
Regenxbio
RGNX
$451M
$13.7M 1.26% 351,954 – –
MTEM
20
DELISTED
Molecular Templates, Inc.
MTEM
$10.7M 0.99% 1,374,047 – –
GRTS
21
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
$9.41M 0.87% 1,030,878 – –
EPIX icon
22
ESSA Pharma
EPIX
$11.4M
$9.05M 0.83% 316,616 – –
ACRS icon
23
Aclaris Therapeutics
ACRS
$209M
$6.51M 0.6% 370,733 -325,267 -47% -$5.71M
EPZM
24
DELISTED
Epizyme, Inc
EPZM
$6.14M 0.57% 739,369 – –
APTX
25
DELISTED
Aptinyx Inc. Common Stock
APTX
$5.33M 0.49% 1,883,244 -1,306,835 -41% -$3.7M
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