FM

Frazier Management Portfolio holdings

AUM $1.12M
This Quarter Return
+3.35%
1 Year Return
+150.24%
3 Year Return
+430.4%
5 Year Return
+1,926.83%
10 Year Return
–
AUM
$1.3B
AUM Growth
+$1.3B
Cap. Flow
+$156M
Cap. Flow %
11.99%
Top 10 Hldgs %
55.9%
Holding
47
New
6
Increased
12
Reduced
2
Closed
4

Top Buys

1
PRDS
Pardes Biosciences, Inc. Common Stock
PRDS
$40.2M
2
SNDX icon
Syndax Pharmaceuticals
SNDX
$34.7M
3
SLN
Silence Therapeutics
SLN
$21.2M
4
MRUS icon
Merus
MRUS
$17.8M
5
TCDA
Tricida, Inc. Common Stock
TCDA
$17.1M

Top Sells

1
TRIL
Trillium Therapeutics Inc.
TRIL
$55M
2
IOVA icon
Iovance Biotherapeutics
IOVA
$17.7M
3
BLU
BELLUS Health Inc.
BLU
$2.65M
4
GRTX
Galera Therapeutics, Inc. Common Stock
GRTX
$1.95M
5
FRLN
Freeline Therapeutics Holdings plc American Depositary Shares
FRLN
$1.88M

Sector Composition

1 Healthcare 98.85%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ARQT icon
1
Arcutis Biotherapeutics
ARQT
$1.86B
$175M 13.47% 8,434,232 – –
PHAT icon
2
Phathom Pharmaceuticals
PHAT
$864M
$115M 8.82% 5,827,415 – –
IMGO
3
DELISTED
Imago BioSciences, Inc. Common stock
IMGO
$70.4M 5.42% 2,971,274 – –
SNDX icon
4
Syndax Pharmaceuticals
SNDX
$1.41B
$60.7M 4.67% 2,772,062 +1,583,927 +133% +$34.7M
GRTS
5
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
$60M 4.62% 4,667,242 – –
MIRM icon
6
Mirum Pharmaceuticals
MIRM
$3.71B
$56.9M 4.38% 3,566,912 – –
PCVX icon
7
Vaxcyte
PCVX
$4B
$54.9M 4.23% 2,309,554 – –
KRYS icon
8
Krystal Biotech
KRYS
$4.27B
$53.9M 4.15% 771,250 – –
PRDS
9
DELISTED
Pardes Biosciences, Inc. Common Stock
PRDS
$40.2M 3.1% +2,457,507 New +$40.2M
CRNX icon
10
Crinetics Pharmaceuticals
CRNX
$2.92B
$39.3M 3.03% 1,384,293 +532,987 +63% +$15.1M
KDNY
11
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$38.7M 2.98% 2,371,918 +700,000 +42% +$11.4M
BCYC
12
Bicycle Therapeutics
BCYC
$511M
$33.8M 2.6% 555,240 +112,360 +25% +$6.84M
IOVA icon
13
Iovance Biotherapeutics
IOVA
$807M
$33.4M 2.57% 1,747,622 -926,677 -35% -$17.7M
TARS icon
14
Tarsus Pharmaceuticals
TARS
$2.47B
$31.9M 2.45% 1,417,157 – –
PASG icon
15
Passage Bio
PASG
$22.7M
$31.8M 2.45% 5,009,219 – –
ANAB icon
16
AnaptysBio
ANAB
$569M
$31.3M 2.41% 899,700 – –
ISEE
17
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$30.7M 2.37% 1,838,402 – –
VRDN icon
18
Viridian Therapeutics
VRDN
$1.5B
$29.8M 2.29% 1,505,200 – –
SRRA
19
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$27.5M 2.12% 1,264,861 +460,194 +57% +$10M
STRO icon
20
Sutro Biopharma
STRO
$72.7M
$26.4M 2.04% 1,776,479 +307,816 +21% +$4.58M
ALPN
21
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$24.7M 1.9% 1,784,913 +13,069 +0.7% +$181K
SLN
22
Silence Therapeutics
SLN
$227M
$21.2M 1.63% +886,173 New +$21.2M
AUTL
23
Autolus Therapeutics
AUTL
$399M
$19.4M 1.5% 3,746,857 +216,200 +6% +$1.12M
MRUS icon
24
Merus
MRUS
$4.98B
$17.8M 1.37% +559,179 New +$17.8M
REPL icon
25
Replimune Group
REPL
$422M
$17.6M 1.36% 650,862 +158,864 +32% +$4.31M
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