Frazier Management’s Krystal Biotech KRYS Stock Holding History

Quarter	Market Value	Status	Shares	Shares Change %	Trade Value	Portfolio Weight	Portfolio Position
2022 Q1	–	Sell	-771,250	Closed	-$53.9M	–	16
2021 Q4	$53.9M	Hold	771,250	–	–	4.15%	8
2021 Q3	$40.3M	Sell	771,250 -16,626	-2%	-$868K	3.22%	10
2021 Q2	$53.6M	Sell	787,876 -107,124	-12%	-$7.28M	4.94%	7
2021 Q1	$69M	Hold	895,000	–	–	5.53%	5
2020 Q4	$53.7M	Hold	895,000	–	–	4.14%	8
2020 Q3	$38.5M	Hold	895,000	–	–	3.46%	8
2020 Q2	$37.1M	Hold	895,000	–	–	3.26%	8
2020 Q1	$38.7M	Hold	895,000	–	–	4.39%	6
2019 Q4	$49.6M	Hold	895,000	–	–	8.31%	3
2019 Q3	$31.1M	Hold	895,000	–	–	9.72%	4
2019 Q2	$36M	Buy	895,000 +20,000	+2%	+$805K	9.24%	3
2019 Q1	$28.8M	Hold	875,000	–	–	6.93%	2
2018 Q4	$18.2M	Buy	875,000 +250,000	+40%	+$5.2M	4.69%	6
2018 Q3	$11M	Buy	+625,000	New	+$11M	2.01%	12