David Shaw’s Ionis Pharmaceuticals IONS Stock Holding History

David Shaw’s Portfolio IONS Stock Details IONS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$6.94M	Buy	+87,500	New	+$6.58M	﹤0.01%	2149
2021 Q1	–	Sell	-38,900	Closed	-$2.2M	–	4260
2020 Q4	$2.2M	Hold	38,900	–	–	﹤0.01%	2495
2020 Q3	$1.85M	Hold	38,900	–	–	﹤0.01%	2459
2020 Q2	$2.29M	Hold	38,900	–	–	﹤0.01%	2310
2020 Q1	$1.84M	Hold	38,900	–	–	﹤0.01%	2236
2019 Q4	$2.35M	Hold	38,900	–	–	﹤0.01%	2336
2019 Q3	$2.33M	Hold	38,900	–	–	﹤0.01%	2242
2019 Q2	$2.5M	Buy	38,900 +8,900	+30%	+$629K	﹤0.01%	2081
2019 Q1	$2.44M	Buy	+30,000	New	+$1.94M	﹤0.01%	2021
2016 Q1	–	Sell	-8,200	Closed	-$508K	–	3592
2015 Q4	$508K	Hold	8,200	–	–	﹤0.01%	3080
2015 Q3	$331K	Hold	8,200	–	–	﹤0.01%	3307
2015 Q2	$472K	Sell	8,200 -5,000	-38%	-$318K	﹤0.01%	3192
2015 Q1	$840K	Sell	13,200 -28,600	-68%	-$1.94M	﹤0.01%	2700
2014 Q4	$2.58M	Buy	41,800 +5,000	+14%	+$247K	﹤0.01%	2066
2014 Q3	$1.43M	Sell	36,800 -8,100	-18%	-$287K	﹤0.01%	2501
2014 Q2	$1.55M	Sell	44,900 -30,000	-40%	-$945K	﹤0.01%	2542
2014 Q1	$3.24M	Buy	74,900 +26,700	+55%	+$1.29M	﹤0.01%	1929
2013 Q4	$1.92M	Buy	48,200 +8,200	+21%	+$292K	﹤0.01%	2566
2013 Q3	$1.5M	Buy	+40,000	New	+$1.19M	﹤0.01%	2679

Other funds holding IONS

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return

Royal Bank of Canada Toronto, Ontario, Canada $672B AUM 33.48% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

T. Rowe Price Investment Management Baltimore, Maryland $153B AUM 38.14% 1-Year Est. Return

David Shaw's IONS Position: Q2 2026 in Review

David Shaw reduced its Ionis Pharmaceuticals (IONS) stake by 31% in Q2 2026, selling an estimated $9.98M and leaving 297,041 shares worth $23.6M. The position accounts for 0.01% of the portfolio, ranked #1187.

David Shaw first reported a position in IONS in Q2 2013 and has held it in 46 quarters since. The position peaked at $49.7M in Q3 2019. 511 funds tracked by Wall St. Rank hold IONS as of Q2 2026.

David Shaw held 297,041 shares of Ionis Pharmaceuticals worth $23.6M as of Q2 2026.
David Shaw sold 132,558 Ionis Pharmaceuticals shares in Q2 2026, an estimated $9.98M.
Ionis Pharmaceuticals made up 0.01% of David Shaw's portfolio in Q2 2026, its #1187 holding.
David Shaw first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 46 quarters since.
David Shaw's Ionis Pharmaceuticals position peaked at $49.7M in Q3 2019.
511 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.