D.E. Shaw & Co
TWST icon

D.E. Shaw & Co’s Twist Bioscience TWST Stock Holding History

D.E. Shaw & Co’s Portfolio TWST Stock Details TWST Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2022
Q4 		– Sell
-20,000
Closed -$705K – 5136
2022
Q3 		$705K Hold
20,000
– – ﹤0.01% 3831
2022
Q2 		$699K Buy
+20,000
New +$708K ﹤0.01% 3858

Other funds holding TWST

Artisan Partners
Artisan Partners Milwaukee, Wisconsin $62.3B AUM 26.25% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $12.9B AUM 64.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
EIG
EdgePoint Investment Group Toronto, Ontario, Canada $12.5B AUM 31.7% 1-Year Est. Return
William Blair Investment Management
William Blair Investment Management Chicago, Illinois $30.3B AUM 33.75% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

D.E. Shaw & Co's TWST Position: Q1 2026 in Review

D.E. Shaw & Co increased its Twist Bioscience (TWST) stake by 69% in Q1 2026, buying an estimated $855K and bringing the position to 46,644 shares worth $2.22M. The position accounts for ﹤0.01% of the portfolio, ranked #2838.

D.E. Shaw & Co first reported a position in TWST in Q4 2018 and has held it in 22 quarters since. The position peaked at $73.8M in Q4 2020. 279 funds tracked by Wall St. Rank hold TWST as of Q1 2026.

  • D.E. Shaw & Co held 46,644 shares of Twist Bioscience worth $2.22M as of Q1 2026.
  • D.E. Shaw & Co bought 19,063 Twist Bioscience shares in Q1 2026, an estimated $855K.
  • Twist Bioscience made up ﹤0.01% of D.E. Shaw & Co's portfolio in Q1 2026, its #2838 holding.
  • D.E. Shaw & Co first reported a position in Twist Bioscience in Q4 2018 and has held it in 22 quarters since.
  • D.E. Shaw & Co's Twist Bioscience position peaked at $73.8M in Q4 2020.
  • 279 funds tracked by Wall St. Rank held Twist Bioscience as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.