D.E. Shaw & Co
REPL icon

D.E. Shaw & Co’s Replimune Group REPL Stock Holding History

D.E. Shaw & Co’s Portfolio REPL Stock Details REPL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$17.9M Sell
2,336,528
-238,514
-9% -$1.82M 0.01% 1231
2025
Q4 		$25M Buy
2,575,042
+2,171,547
+538% +$18.5M 0.01% 1110
2025
Q3 		$1.69M Sell
403,495
-103,101
-20% -$659K ﹤0.01% 3089
2025
Q2 		$4.71M Sell
506,596
-289,984
-36% -$2.53M ﹤0.01% 2085
2025
Q1 		$7.77M Sell
796,580
-175,995
-18% -$2.18M 0.01% 1576
2024
Q4 		$11.8M Buy
972,575
+104,892
+12% +$1.27M 0.01% 1397
2024
Q3 		$9.51M Sell
867,683
-64,097
-7% -$651K 0.01% 1458
2024
Q2 		$8.39M Sell
931,780
-66,006
-7% -$460K 0.01% 1443
2024
Q1 		$8.15M Buy
997,786
+754,780
+311% +$6.19M 0.01% 1518
2023
Q4 		$2.05M Buy
243,006
+162,303
+201% +$1.88M ﹤0.01% 2645
2023
Q3 		$1.38M Sell
80,703
-6,879
-8% -$135K ﹤0.01% 2862
2023
Q2 		$2.03M Sell
87,582
-48,557
-36% -$949K ﹤0.01% 2609
2023
Q1 		$2.4M Buy
136,139
+7,170
+6% +$171K ﹤0.01% 2551
2022
Q4 		$3.51M Buy
+128,969
New +$2.68M ﹤0.01% 2427
2022
Q2 		– Sell
-18,922
Closed -$321K – 5694
2022
Q1 		$321K Buy
+18,922
New +$357K ﹤0.01% 4617
2021
Q2 		– Sell
-121,257
Closed -$3.7M – 4973
2021
Q1 		$3.7M Buy
121,257
+14,098
+13% +$528K ﹤0.01% 2084
2020
Q4 		$4.09M Buy
107,159
+79,163
+283% +$3.3M ﹤0.01% 2029
2020
Q3 		$644K Buy
+27,996
New +$638K ﹤0.01% 3097

Other funds holding REPL

BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
SCM
Suvretta Capital Management New York $3.92B AUM 86.67% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
FIS
FCPM III Services Naarden, Netherlands $722M AUM 73.61% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

D.E. Shaw & Co's REPL Position: Q1 2026 in Review

D.E. Shaw & Co reduced its Replimune Group (REPL) stake by 9.3% in Q1 2026, selling an estimated $1.82M and leaving 2,336,528 shares worth $17.9M. The position accounts for 0.01% of the portfolio, ranked #1231.

D.E. Shaw & Co first reported a position in REPL in Q3 2020 and has held it in 18 quarters since. The position peaked at $25M in Q4 2025. 180 funds tracked by Wall St. Rank hold REPL as of Q1 2026.

  • D.E. Shaw & Co held 2,336,528 shares of Replimune Group worth $17.9M as of Q1 2026.
  • D.E. Shaw & Co sold 238,514 Replimune Group shares in Q1 2026, an estimated $1.82M.
  • Replimune Group made up 0.01% of D.E. Shaw & Co's portfolio in Q1 2026, its #1231 holding.
  • D.E. Shaw & Co first reported a position in Replimune Group in Q3 2020 and has held it in 18 quarters since.
  • D.E. Shaw & Co's Replimune Group position peaked at $25M in Q4 2025.
  • 180 funds tracked by Wall St. Rank held Replimune Group as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.