Replimune Group
REPL
180 hedge funds and large institutions have $619M invested in Replimune Group in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 61 increasing their positions, 49 reducing their positions, and 29 closing their positions.
213% more call options, than puts
Call options by funds: $46.8M | Put options by funds: $14.9M
62% more first-time investments, than exits
New positions opened: 47 | Existing positions closed: 29
24% more repeat investments, than reductions
Existing positions increased: 61 | Existing positions reduced: 49
10% more funds holding
Funds holding: 164 → 180 (+16)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
3.45% less ownership
Funds ownership: 101.66% → 98.21% (-3.4%)
20% less capital invested
Capital invested by funds: $775M → $619M (-$156M)
Top Buyers
| 1 |
SCM
Suvretta Capital Management
New York
|
+$32M |
| 2 |
Goldman Sachs
New York
|
+$12.4M |
| 3 |
EC
EcoR1 Capital
San Francisco,
California
|
+$7.64M |
| 4 |
SCM
Sio Capital Management
New York
|
+$5.5M |
| 5 |
BCM
Boxer Capital Management
San Diego,
California
|
+$3.25M |
Top Sellers
| 1 |
CC
Commodore Capital
New York
|
-$13.9M |
| 2 |
Adage Capital Partners
Boston,
Massachusetts
|
-$11.5M |
| 3 |
RA
Rosalind Advisors
Toronto,
Ontario, Canada
|
-$10.8M |
| 4 |
RG
Redmile Group
San Francisco,
California
|
-$10.7M |
| 5 |
Fidelity Investments
Boston,
Massachusetts
|
-$7.16M |
REPL Hedge Fund Activity: Q1 2026 in Review
180 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Replimune Group (REPL) for Q1 2026, worth a combined $619M — down 20% from $775M a quarter earlier.
Buyers outnumbered sellers: 47 funds opened new REPL positions and 29 closed out — a net gain of 18 holders — while 61 added to existing stakes and 49 trimmed.
The largest buyer was Suvretta Capital Management, adding an estimated $32M. The largest seller was Commodore Capital, exiting entirely with an estimated $13.9M sold.
- 180 institutional investors held Replimune Group (REPL) as of Q1 2026, up from 164 in Q4 2025.
- Funds reported $619M of Replimune Group stock for Q1 2026, down 20% quarter-over-quarter.
- 47 funds opened new Replimune Group positions in Q1 2026 and 29 closed out, a net change of +18 holders.
- The largest Replimune Group buyer in Q1 2026 was Suvretta Capital Management, an estimated $32M added.
- The largest Replimune Group seller in Q1 2026 was Commodore Capital, an estimated $13.9M sold.
Based on aggregated 13F filings for Q1 2026.