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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
URI icon
301
United Rentals
URI
$72.4B
$40.6M 0.06%
50,171
+1,002
+2% +$870K
TEAM icon
302
Atlassian
TEAM
$28B
$40.5M 0.06%
250,000
-25,000
-9% -$3.92M
TECK icon
303
Teck Resources
TECK
$32.4B
$40.5M 0.06%
+846,169
New +$36.7M
AXON
304
Axon Enterprise
AXON
$42.1B
$40.4M 0.06%
71,200
-200
-0.3% -$124K
TTWO icon
305
Take-Two Interactive
TTWO
$43.5B
$40.1M 0.06%
156,760
-1,100
-0.7% -$274K
FTNT icon
306
Fortinet
FTNT
$117B
$39.4M 0.06%
495,690
+3,400
+0.7% +$282K
KMB icon
307
Kimberly-Clark
KMB
$36.1B
$39.3M 0.06%
389,633
+113,600
+41% +$12.4M
HCC icon
308
Warrior Met Coal
HCC
$4.73B
$39.2M 0.06%
445,000
-530,000
-54% -$39.8M
PYPL icon
309
PayPal
PYPL
$51.1B
$39.2M 0.06%
670,675
-108,000
-14% -$7.01M
MIAX
310
Miami International Holdings
MIAX
$4.4B
$39.1M 0.06%
881,329
+249,677
+40% +$11.1M
BBIO icon
311
BridgeBio Pharma
BBIO
$16.2B
$38.9M 0.06%
508,134
-436,712
-46% -$28.7M
LDOS icon
312
Leidos
LDOS
$17B
$38.9M 0.06%
215,400
+81,738
+61% +$15.5M
COHR icon
313
Coherent
COHR
$65.4B
$38.8M 0.06%
210,000
-115,000
-35% -$17.2M
SYK icon
314
Stryker
SYK
$129B
$38.6M 0.06%
109,720
-69,139
-39% -$25.2M
TKR icon
315
Timken Company
TKR
$8.92B
$38.4M 0.06%
+456,905
New +$36.3M
THC icon
316
Tenet Healthcare
THC
$20.7B
$38.1M 0.06%
191,854
-203,661
-51% -$41.2M
GWW icon
317
W.W. Grainger
GWW
$60.4B
$37.9M 0.06%
37,542
-2,500
-6% -$2.42M
GTLS
318
DELISTED
Chart Industries
GTLS
$37.9M 0.06%
183,603
+50,000
+37% +$10.1M
ESI icon
319
Element Solutions
ESI
$9.37B
$37.8M 0.06%
1,513,000
+783,000
+107% +$20.3M
AME icon
320
Ametek
AME
$57.6B
$37.5M 0.06%
182,841
-39,752
-18% -$7.73M
MIRM icon
321
Mirum Pharmaceuticals
MIRM
$5.74B
$36.9M 0.06%
467,468
-30,000
-6% -$2.15M
LH icon
322
Labcorp
LH
$25.6B
$36.9M 0.06%
147,000
+123,300
+520% +$32.7M
ARWR icon
323
Arrowhead Research
ARWR
$12.1B
$36.5M 0.06%
+550,000
New +$27M
WAY
324
Waystar Holding Corp
WAY
$4.48B
$36.2M 0.05%
1,105,454
+421,220
+62% +$15M
FICO icon
325
Fair Isaac
FICO
$22.3B
$36.2M 0.05%
21,400
-400
-2% -$689K
11 12
13
14 15

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.