Adage Capital Partners’s Arrowhead Research ARWR Stock Holding History

Adage Capital Partners’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-550,000	Closed	-$36.5M	–	964
2025 Q4	$36.5M	Buy	+550,000	New	+$27M	0.06%	323
2024 Q4	–	Sell	-350,000	Closed	-$6.78M	–	877
2024 Q3	$6.78M	Buy	350,000 +250,000	+250%	+$6.1M	0.01%	680
2024 Q2	$2.6M	Buy	+100,000	New	+$2.46M	﹤0.01%	767
2023 Q4	–	Sell	-103,035	Closed	-$2.77M	–	855
2023 Q3	$2.77M	Sell	103,035 -15,000	-13%	-$460K	0.01%	723
2023 Q2	$4.21M	Buy	118,035 +30,316	+35%	+$1.05M	0.01%	687
2023 Q1	$2.23M	Sell	87,719 -7,800	-8%	-$245K	0.01%	758
2022 Q4	$3.87M	Buy	95,519 +82,620	+641%	+$2.74M	0.01%	771
2022 Q3	$426K	Hold	12,899	–	–	﹤0.01%	918
2022 Q2	$454K	Sell	12,899 -10,700	-45%	-$403K	﹤0.01%	942
2022 Q1	$1.08M	Sell	23,599 -116,401	-83%	-$5.76M	﹤0.01%	933
2021 Q4	$9.28M	Hold	140,000	–	–	0.02%	721
2021 Q3	$8.74M	Sell	140,000 -10,000	-7%	-$647K	0.02%	730
2021 Q2	$12.4M	Buy	150,000 +110,000	+275%	+$8.19M	0.02%	637
2021 Q1	$2.65M	Sell	40,000 -110,000	-73%	-$8.54M	0.01%	843
2020 Q4	$11.5M	Buy	150,000 +50,000	+50%	+$3.2M	0.03%	556
2020 Q3	$4.31M	Sell	100,000 -25,000	-20%	-$1.08M	0.01%	657
2020 Q2	$5.4M	Sell	125,000 -25,000	-17%	-$882K	0.01%	610
2020 Q1	$4.32M	Sell	150,000 -25,000	-14%	-$1.01M	0.01%	593
2019 Q4	$11.1M	Sell	175,000 -250,000	-59%	-$12.4M	0.03%	522
2019 Q3	$12M	Sell	425,000 -450,000	-51%	-$13.3M	0.03%	483
2019 Q2	$23.2M	Sell	875,000 -500,000	-36%	-$11M	0.06%	335
2019 Q1	$25.2M	Hold	1,375,000	–	–	0.06%	330
2018 Q4	$17.1M	Buy	1,375,000 +475,000	+53%	+$6.49M	0.05%	372
2018 Q3	$17.3M	Sell	900,000 -603,500	-40%	-$9.9M	0.04%	442
2018 Q2	$20.4M	Hold	1,503,500	–	–	0.05%	394
2018 Q1	$10.8M	Buy	+1,503,500	New	+$9.26M	0.03%	541

Other funds holding ARWR

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

FAM

Fred Alger Management New York $22.8B AUM 64.63% 1-Year Est. Return

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

VPC

Vestal Point Capital New York $3.58B AUM 189.12% 1-Year Est. Return

Adage Capital Partners's ARWR Position: Q1 2026 in Review

Adage Capital Partners sold out of Arrowhead Research (ARWR) in Q1 2026, closing a stake of 550,000 shares — an estimated $36.5M sold.

Adage Capital Partners first reported a position in ARWR in Q1 2018 and held it in 26 quarters. The position peaked at $36.5M in Q4 2025. 436 funds tracked by Wall St. Rank hold ARWR as of Q1 2026.

Adage Capital Partners reported no remaining Arrowhead Research position as of Q1 2026 after selling out during the quarter.
Adage Capital Partners sold 550,000 Arrowhead Research shares in Q1 2026, an estimated $36.5M.
Adage Capital Partners first reported a position in Arrowhead Research in Q1 2018 and held it in 26 quarters.
Adage Capital Partners's Arrowhead Research position peaked at $36.5M in Q4 2025.
436 funds tracked by Wall St. Rank held Arrowhead Research as of Q1 2026.

Based on Adage Capital Partners's 13F filing for Q1 2026, filed 15 May 2026.