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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NVDA icon
1
NVIDIA
NVDA
$5.01T
$4.15B 6.28%
22,258,110
-250,000
-1% -$46.5M
AAPL icon
2
Apple
AAPL
$4.89T
$3.6B 5.44%
13,226,554
-140,100
-1% -$37.6M
MSFT icon
3
Microsoft
MSFT
$2.84T
$3.21B 4.85%
6,627,143
-153,200
-2% -$76.8M
AMZN icon
4
Amazon
AMZN
$2.5T
$2.09B 3.17%
9,064,760
-261,600
-3% -$59.9M
GOOGL icon
5
Alphabet (Google) Class A
GOOGL
$3.91T
$1.64B 2.49%
5,253,800
-35,900
-0.7% -$10.3M
AVGO icon
6
Broadcom
AVGO
$1.82T
$1.46B 2.21%
4,222,056
+17,300
+0.4% +$6.19M
META icon
7
Meta Platforms (Facebook)
META
$1.51T
$1.33B 2.01%
2,016,435
+20,100
+1% +$13.4M
GOOG icon
8
Alphabet (Google) Class C
GOOG
$3.9T
$1.31B 1.98%
4,179,120
-142,400
-3% -$40.8M
TSLA icon
9
Tesla
TSLA
$1.24T
$1.11B 1.68%
2,472,800
+20,300
+0.8% +$9M
LLY icon
10
Eli Lilly
LLY
$1.07T
$894M 1.35%
832,292
+25,426
+3% +$24.3M
BRK.B icon
11
Berkshire Hathaway Class B
BRK.B
$1.07T
$826M 1.25%
1,643,469
-2,000
-0.1% -$995K
JPM icon
12
JPMorgan Chase
JPM
$939B
$783M 1.18%
2,428,466
-10,000
-0.4% -$3.1M
COP icon
13
ConocoPhillips
COP
$147B
$659M 1%
7,037,277
+1,104,900
+19% +$99.9M
V icon
14
Visa
V
$677B
$529M 0.8%
1,507,340
-25,200
-2% -$8.59M
JNJ icon
15
Johnson & Johnson
JNJ
$634B
$458M 0.69%
2,210,913
-52,744
-2% -$10.4M
RPRX icon
16
Royalty Pharma
RPRX
$26.1B
$454M 0.69%
11,740,594
-225,039
-2% -$8.58M
WMT icon
17
Walmart Inc
WMT
$871B
$432M 0.65%
3,873,326
-100,200
-3% -$10.8M
MA icon
18
Mastercard
MA
$477B
$417M 0.63%
730,560
-16,050
-2% -$8.97M
PG icon
19
Procter & Gamble
PG
$343B
$404M 0.61%
2,822,220
-962,853
-25% -$142M
NFLX icon
20
Netflix
NFLX
$292B
$378M 0.57%
4,035,830
+334,500
+9% +$36.1M
PLTR icon
21
Palantir
PLTR
$295B
$367M 0.56%
2,064,600
-3,500
-0.2% -$634K
HD icon
22
Home Depot
HD
$332B
$365M 0.55%
1,061,656
-99,100
-9% -$36.3M
ORCL icon
23
Oracle
ORCL
$331B
$365M 0.55%
1,870,116
+303,100
+19% +$72.2M
BAC icon
24
Bank of America
BAC
$435B
$358M 0.54%
6,505,273
-811,400
-11% -$42.9M
ABBV icon
25
AbbVie
ABBV
$458B
$345M 0.52%
1,508,715
-336,077
-18% -$76.6M
1
2 3 4 5

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.