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5VM

5AM Venture Management Portfolio holdings

AUM $360M
1-Year Est. Return 345.76%
This Fund
S&P 500
This Quarter Est. Return
+44.76%
1 Year Est. Return
+345.76%
3 Year Est. Return
+491.51%
5 Year Est. Return
+330.26%
10 Year Est. Return
–
AUM
$522M
AUM Growth
+$118M
Cap. Flow
+$942K
Cap. Flow %
0.18%
Top 10 Hldgs %
85.75%
Holding
23
New
2
Increased
1
Reduced
5
Closed
2

Top Buys

Rank Stock Value
1
CINC
CinCor Pharma, Inc. Common Stock
CINC
+$17M
2
VRDN icon
Viridian Therapeutics
VRDN
+$8.72M
3
IRON icon
Disc Medicine
IRON
+$825K

Top Sells

Rank Stock Value
1
ISEE
IVERIC bio, Inc. Common Stock
ISEE
+$6.81M
2
RXDX
Prometheus Biosciences, Inc. Common Stock
RXDX
+$5.15M
3
COGT icon
Cogent Biosciences
COGT
+$4.64M
4
PEAR
Pear Therapeutics, Inc. Class A Common Stock
PEAR
+$2.93M
5
IDYA icon
IDEAYA Biosciences
IDYA
+$2.62M

Sector Composition

Rank Sector Weight
1 Healthcare 99.3%
2 Financials 0.7%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CINC
1
DELISTED
CinCor Pharma, Inc. Common Stock
CINC
$162M 31.05%
4,937,646
+600,000
+14% +$17M
TRDA icon
2
Entrada Therapeutics
TRDA
$263M
$69.5M 13.31%
4,408,379
– –
RLYB icon
3
Rallybio
RLYB
$85.3M
$54M 10.34%
466,341
– –
PEAR
4
DELISTED
Pear Therapeutics, Inc. Class A Common Stock
PEAR
$34.5M 6.61%
16,903,603
-1,728,168
-9% -$2.93M
AKUS
5
DELISTED
Akouos Inc
AKUS
$28M 5.36%
4,135,784
– –
VOR icon
6
Vor Biopharma
VOR
$1.18B
$25.3M 4.85%
318,086
– –
SCPH
7
DELISTED
scPharmaceuticals
SCPH
$21.7M 4.17%
3,334,852
-226,622
-6% -$1.21M
IDYA icon
8
IDEAYA Biosciences
IDYA
$3.5B
$17.8M 3.42%
1,196,298
-201,768
-14% -$2.62M
ARVN icon
9
Arvinas
ARVN
$536M
$17.8M 3.41%
400,000
– –
CRNX icon
10
Crinetics Pharmaceuticals
CRNX
$8.85B
$16.9M 3.24%
862,286
– –
IMPL
11
DELISTED
Impel Pharmaceuticals Inc. Common Stock
IMPL
$14M 2.69%
2,884,791
– –
COGT icon
12
Cogent Biosciences
COGT
$7.07B
$11.8M 2.26%
790,440
-338,760
-30% -$4.64M
VRDN icon
13
Viridian Therapeutics
VRDN
$2.2B
$9.95M 1.91%
+484,891
New +$8.72M
ISEE
14
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$9.13M 1.75%
508,847
-519,027
-50% -$6.81M
QTTB icon
15
Q32 Bio
QTTB
$462M
$7.3M 1.4%
251,996
– –
RNAM
16
DELISTED
Avidity Biosciences
RNAM
$6.38M 1.22%
390,555
– –
JANX icon
17
Janux Therapeutics
JANX
$950M
$6.04M 1.16%
446,266
– –
PHVS icon
18
Pharvaris
PHVS
$2.37B
$4.51M 0.86%
587,600
– –
FVAM
19
DELISTED
5:01 Acquisition Corp
FVAM
$3.65M 0.7%
365,126
– –
IRON icon
20
Disc Medicine
IRON
$3.03B
$860K 0.16%
+17,483
New +$825K
CDTX
21
DELISTED
Cidara Therapeutics
CDTX
$712K 0.14%
56,726
– –
CABA icon
22
Cabaletta Bio
CABA
$444M
– –
-2,064,263
Closed -$2.19M
RXDX
23
DELISTED
Prometheus Biosciences, Inc. Common Stock
RXDX
– –
-182,370
Closed -$5.15M

Similar funds

LSC
Logan Stone Capital Chicago, Illinois $360M AUM 9.71% 1-Year Est. Return
WIP
WealthCare Investment Partners Portsmouth, Rhode Island $360M AUM 19.98% 1-Year Est. Return
RA
RR Advisors Dallas, Texas $360M AUM 28.52% 1-Year Est. Return
SWM
SK Wealth Management Providence, Rhode Island $360M AUM 14.81% 1-Year Est. Return
NC
Naman Capital Sao Paulo, Brazil $360M AUM 27.43% 1-Year Est. Return
MCM
Monimus Capital Management Woodbridge, New Jersey $361M AUM 21.17% 1-Year Est. Return
KLWA
Kelly Lawrence W & Associates Pasadens, California $360M AUM 16.9% 1-Year Est. Return
PWC
PYA Waltman Capital Knoxville, Tennessee $361M AUM 9.49% 1-Year Est. Return

5AM Venture Management's Q3 2022 Portfolio in Review

As of Q3 2022, 5AM Venture Management held 23 positions worth $522M, up 29% from $404M the previous quarter. Its ten largest holdings account for 86% of the portfolio.

5AM Venture Management's Q3 2022 filing shows 2 new, 1 increased, 5 reduced and 2 closed positions. Its largest new stake was Viridian Therapeutics: 484,891 shares worth $9.95M. The largest sale was IVERIC bio, Inc. Common Stock, an estimated $6.81M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Financials.

  • 5AM Venture Management's largest Q3 2022 buy was Viridian Therapeutics: 484,891 shares worth $9.95M.
  • 5AM Venture Management added most to CinCor Pharma, Inc. Common Stock in Q3 2022, an estimated $17M increase.
  • 5AM Venture Management's biggest Q3 2022 reduction was IVERIC bio, Inc. Common Stock, cutting an estimated $6.81M.
  • 5AM Venture Management fully exited Prometheus Biosciences, Inc. Common Stock in Q3 2022, selling an estimated $5.15M.
  • 5AM Venture Management's ten largest holdings make up 86% of its $522M portfolio in Q3 2022.
  • 5AM Venture Management opened 2 new positions and closed 2 in Q3 2022.
  • 5AM Venture Management's portfolio value rose 29% quarter-over-quarter to $522M.

Based on 5AM Venture Management's 13F filing for Q3 2022, filed 14 Nov 2022.