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5VM

5AM Venture Management Portfolio holdings

AUM $360M
1-Year Est. Return 345.76%
This Fund
S&P 500
This Quarter Est. Return
+8.37%
1 Year Est. Return
+345.76%
3 Year Est. Return
+491.51%
5 Year Est. Return
+330.26%
10 Year Est. Return
–
AUM
$555M
AUM Growth
+$258M
Cap. Flow
+$274M
Cap. Flow %
49.33%
Top 10 Hldgs %
99.43%
Holding
11
New
1
Increased
–
Reduced
2
Closed
–

Top Buys

Rank Stock Value
1
VOR icon
Vor Biopharma
VOR
+$283M

Top Sells

Rank Stock Value
1
CABA icon
Cabaletta Bio
CABA
+$4.73M
2
APRE icon
Aprea Therapeutics
APRE
+$4.42M

Sector Composition

Rank Sector Weight
1 Healthcare 99.34%
2 Financials 0.66%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VOR icon
1
Vor Biopharma
VOR
$1.16B
$288M 51.94%
+334,621
New +$283M
AKUS
2
DELISTED
Akouos Inc
AKUS
$57.4M 10.33%
4,135,784
– –
QTTB icon
3
Q32 Bio
QTTB
$450M
$42.7M 7.69%
251,996
– –
IDYA icon
4
IDEAYA Biosciences
IDYA
$3.41B
$42.3M 7.61%
1,798,066
– –
CABA icon
5
Cabaletta Bio
CABA
$439M
$33.1M 5.96%
2,984,263
-387,000
-11% -$4.73M
ARVN icon
6
Arvinas
ARVN
$520M
$33M 5.95%
500,000
– –
SCPH
7
DELISTED
scPharmaceuticals
SCPH
$25.5M 4.59%
3,831,474
– –
CRNX icon
8
Crinetics Pharmaceuticals
CRNX
$8.89B
$20.8M 3.75%
1,362,286
– –
CDTX
9
DELISTED
Cidara Therapeutics
CDTX
$5.34M 0.96%
100,326
– –
FVAM
10
DELISTED
5:01 Acquisition Corp
FVAM
$3.65M 0.66%
365,126
– –
APRE icon
11
Aprea Therapeutics
APRE
$7.4M
$3.16M 0.57%
30,958
-37,925
-55% -$4.42M

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RA
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SWM
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NC
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MCM
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KLWA
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5AM Venture Management's Q1 2021 Portfolio in Review

As of Q1 2021, 5AM Venture Management held 11 positions worth $555M, up 87% from $297M the previous quarter. Its ten largest holdings account for 99% of the portfolio.

5AM Venture Management deployed $274M of net new capital in Q1 2021, opening 1 new position. Its largest new stake was Vor Biopharma: 334,621 shares worth $288M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Cabaletta Bio, an estimated $4.73M trimmed.

  • 5AM Venture Management's largest Q1 2021 buy was Vor Biopharma: 334,621 shares worth $288M.
  • 5AM Venture Management's biggest Q1 2021 reduction was Cabaletta Bio, cutting an estimated $4.73M.
  • 5AM Venture Management's ten largest holdings make up 99% of its $555M portfolio in Q1 2021.
  • 5AM Venture Management opened 1 new position and closed 0 in Q1 2021.
  • 5AM Venture Management's portfolio value rose 87% quarter-over-quarter to $555M.

Based on 5AM Venture Management's 13F filing for Q1 2021, filed 17 May 2021.