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5VM

5AM Venture Management Portfolio holdings

AUM $360M
1-Year Est. Return 345.76%
This Fund
S&P 500
This Quarter Est. Return
+11.94%
1 Year Est. Return
+345.76%
3 Year Est. Return
+491.51%
5 Year Est. Return
+330.26%
10 Year Est. Return
–
AUM
$492M
AUM Growth
+$95.1M
Cap. Flow
+$69.3M
Cap. Flow %
14.08%
Top 10 Hldgs %
91.13%
Holding
16
New
4
Increased
–
Reduced
3
Closed
–

Top Buys

Rank Stock Value
1
RLYB icon
Rallybio
RLYB
+$61.4M
2
RNAM
Avidity Biosciences
RNAM
+$12.1M
3
ISEE
IVERIC bio, Inc. Common Stock
ISEE
+$8.38M
4
SPRY icon
ARS Pharmaceuticals
SPRY
+$4.19M

Top Sells

Rank Stock Value
1
IDYA icon
IDEAYA Biosciences
IDYA
+$9.34M
2
CABA icon
Cabaletta Bio
CABA
+$5.76M
3
CDTX
Cidara Therapeutics
CDTX
+$1.66M

Sector Composition

Rank Sector Weight
1 Healthcare 99.27%
2 Financials 0.73%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VOR icon
1
Vor Biopharma
VOR
$1.16B
$105M 21.31%
334,621
– –
RLYB icon
2
Rallybio
RLYB
$84.6M
$73.7M 14.96%
+523,841
New +$61.4M
AKUS
3
DELISTED
Akouos Inc
AKUS
$48M 9.75%
4,135,784
– –
QTTB icon
4
Q32 Bio
QTTB
$450M
$35.7M 7.25%
251,996
– –
IDYA icon
5
IDEAYA Biosciences
IDYA
$3.41B
$35.6M 7.24%
1,398,066
-400,000
-22% -$9.34M
IMPL
6
DELISTED
Impel Pharmaceuticals Inc. Common Stock
IMPL
$35.1M 7.13%
2,884,791
– –
ARVN icon
7
Arvinas
ARVN
$520M
$32.9M 6.67%
400,000
– –
CABA icon
8
Cabaletta Bio
CABA
$439M
$28.7M 5.83%
2,359,263
-625,000
-21% -$5.76M
CRNX icon
9
Crinetics Pharmaceuticals
CRNX
$8.89B
$28.7M 5.82%
1,362,286
– –
SCPH
10
DELISTED
scPharmaceuticals
SCPH
$25.5M 5.17%
3,831,474
– –
RNAM
11
DELISTED
Avidity Biosciences
RNAM
$13.7M 2.78%
+555,555
New +$12.1M
ISEE
12
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$12.5M 2.54%
+770,000
New +$8.38M
JANX icon
13
Janux Therapeutics
JANX
$934M
$9.65M 1.96%
446,266
– –
FVAM
14
DELISTED
5:01 Acquisition Corp
FVAM
$3.59M 0.73%
365,126
– –
CDTX
15
DELISTED
Cidara Therapeutics
CDTX
$2.54M 0.52%
56,726
-43,600
-43% -$1.66M
SPRY icon
16
ARS Pharmaceuticals
SPRY
$542M
$1.69M 0.34%
+169,748
New +$4.19M

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LSC
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WIP
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RA
RR Advisors Dallas, Texas $360M AUM 28.52% 1-Year Est. Return
SWM
SK Wealth Management Providence, Rhode Island $360M AUM 14.81% 1-Year Est. Return
NC
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MCM
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KLWA
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PWC
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5AM Venture Management's Q3 2021 Portfolio in Review

As of Q3 2021, 5AM Venture Management held 16 positions worth $492M, up 24% from $397M the previous quarter. Its ten largest holdings account for 91% of the portfolio.

5AM Venture Management deployed $69.3M of net new capital in Q3 2021, opening 4 new positions. Its largest new stake was Rallybio: 523,841 shares worth $73.7M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was IDEAYA Biosciences, an estimated $9.34M trimmed.

  • 5AM Venture Management's largest Q3 2021 buy was Rallybio: 523,841 shares worth $73.7M.
  • 5AM Venture Management's biggest Q3 2021 reduction was IDEAYA Biosciences, cutting an estimated $9.34M.
  • 5AM Venture Management's ten largest holdings make up 91% of its $492M portfolio in Q3 2021.
  • 5AM Venture Management opened 4 new positions and closed 0 in Q3 2021.
  • 5AM Venture Management's portfolio value rose 24% quarter-over-quarter to $492M.

Based on 5AM Venture Management's 13F filing for Q3 2021, filed 15 Nov 2021.