We are live on ! Find out more
5VM

5AM Venture Management Portfolio holdings

AUM $360M
1-Year Est. Return 345.76%
This Fund
S&P 500
This Quarter Est. Return
+38.38%
1 Year Est. Return
+345.76%
3 Year Est. Return
+491.51%
5 Year Est. Return
+330.26%
10 Year Est. Return
–
AUM
$273M
AUM Growth
+$12.9M
Cap. Flow
-$47.5M
Cap. Flow %
-17.38%
Top 10 Hldgs %
69.92%
Holding
29
New
–
Increased
1
Reduced
4
Closed
4

Top Buys

Rank Stock Value
1
CAMP icon
CAMP4 Therapeutics
CAMP
+$5.45M

Top Sells

Rank Stock Value
1
DNTH icon
Dianthus Therapeutics
DNTH
+$15.8M
2
MLTX icon
MoonLake Immunotherapeutics
MLTX
+$13.3M
3
VOR icon
Vor Biopharma
VOR
+$10.3M
4
VKTX icon
Viking Therapeutics
VKTX
+$5.02M
5
SCPH
scPharmaceuticals
SCPH
+$4.57M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MLTX icon
26
MoonLake Immunotherapeutics
MLTX
$1.5B
– –
-282,313
Closed -$13.3M
SCPH
27
DELISTED
scPharmaceuticals
SCPH
– –
-1,200,647
Closed -$4.57M
VKTX icon
28
Viking Therapeutics
VKTX
$3.9B
– –
-189,593
Closed -$5.02M
VOR icon
29
Vor Biopharma
VOR
$1.21B
– –
-318,086
Closed -$10.3M
1
2

Similar funds

LSC
Logan Stone Capital Chicago, Illinois $360M AUM 9.71% 1-Year Est. Return
WIP
WealthCare Investment Partners Portsmouth, Rhode Island $360M AUM 19.98% 1-Year Est. Return
RA
RR Advisors Dallas, Texas $360M AUM 28.52% 1-Year Est. Return
SWM
SK Wealth Management Providence, Rhode Island $360M AUM 14.81% 1-Year Est. Return
NC
Naman Capital Sao Paulo, Brazil $360M AUM 27.43% 1-Year Est. Return
MCM
Monimus Capital Management Woodbridge, New Jersey $361M AUM 21.17% 1-Year Est. Return
KLWA
Kelly Lawrence W & Associates Pasadens, California $360M AUM 16.9% 1-Year Est. Return
PWC
PYA Waltman Capital Knoxville, Tennessee $361M AUM 9.49% 1-Year Est. Return

5AM Venture Management's Q3 2025 Portfolio in Review

As of Q3 2025, 5AM Venture Management held 29 positions worth $273M, up 5% from $260M the previous quarter. Its ten largest holdings account for 70% of the portfolio.

5AM Venture Management withdrew a net $47.5M in Q3 2025, closing 4 positions and reducing 4 holdings. Its most notable exit was MoonLake Immunotherapeutics, an estimated $13.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

Against the trend, 5AM Venture Management added an estimated $5.45M to CAMP4 Therapeutics.

  • 5AM Venture Management added most to CAMP4 Therapeutics in Q3 2025, an estimated $5.45M increase.
  • 5AM Venture Management's biggest Q3 2025 reduction was Dianthus Therapeutics, cutting an estimated $15.8M.
  • 5AM Venture Management fully exited MoonLake Immunotherapeutics in Q3 2025, selling an estimated $13.3M.
  • 5AM Venture Management's ten largest holdings make up 70% of its $273M portfolio in Q3 2025.
  • 5AM Venture Management opened 0 new positions and closed 4 in Q3 2025.
  • 5AM Venture Management's portfolio value rose 5% quarter-over-quarter to $273M.

Based on 5AM Venture Management's 13F filing for Q3 2025, filed 14 Nov 2025.