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5VM
5AM Venture Management Portfolio holdings
AUM
$288M
1-Year Est. Return
313.93%
This Fund
S&P 500
This Quarter
Est. Return
+22.99%
1 Year Est. Return
+313.93%
3 Year Est. Return
+546.33%
5 Year Est. Return
+596.42%
10 Year Est. Return
–
AUM
$288M
AUM Growth
-$72.3M
(-20%)
Cap. Flow
-$93.3M
Cap. Flow
% of AUM
-32.42%
Top 10 Holdings %
Top 10 Hldgs %
85.57%
Holding
20
New
–
Increased
–
Reduced
1
Closed
4
Top Buys
No buys this quarter
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Erasca
ERAS
|
+$56.4M |
| 2 |
CNTA
Centessa Pharmaceuticals
CNTA
|
+$23.1M |
| 3 |
GH Research
GHRS
|
+$8.05M |
| 4 |
Surrozen
SRZN
|
+$3.19M |
| 5 |
Rallybio
RLYB
|
+$2.62M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 100% |
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5AM Venture Management's Q2 2026 Portfolio in Review
As of Q2 2026, 5AM Venture Management held 20 positions worth $288M, down 20% from $360M the previous quarter. Its ten largest holdings account for 86% of the portfolio.
5AM Venture Management withdrew a net $93.3M in Q2 2026, closing 4 positions and reducing 1 holding. Its most notable exit was Erasca, an estimated $56.4M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.
- 5AM Venture Management's biggest Q2 2026 reduction was Surrozen, cutting an estimated $3.19M.
- 5AM Venture Management fully exited Erasca in Q2 2026, selling an estimated $56.4M.
- 5AM Venture Management's ten largest holdings make up 86% of its $288M portfolio in Q2 2026.
- 5AM Venture Management opened 0 new positions and closed 4 in Q2 2026.
- 5AM Venture Management's portfolio value fell 20% quarter-over-quarter to $288M.
Based on 5AM Venture Management's 13F filing for Q2 2026, filed 14 Aug 2026.