5AM Venture Management’s Alector ALEC Stock Holding History

5AM Venture Management’s Portfolio ALEC Stock Details ALEC Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-995,841	Closed	-$2.95M	–	23
2025 Q3	$2.95M	Hold	995,841	–	–	1.08%	20
2025 Q2	$1.39M	Hold	995,841	–	–	0.54%	25
2025 Q1	$1.22M	Hold	995,841	–	–	0.46%	28
2024 Q4	$1.88M	Buy	+995,841	New	+$3.75M	0.45%	28

Other funds holding ALEC

TCM

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

FCMI

Foresite Capital Management IV Larkspur, California $237M AUM 107.53% 1-Year Est. Return

Merck & Co Kenilworth, New Jersey $349M AUM 146.07% 1-Year Est. Return

Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return

6CM

683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return

Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return

D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

5AM Venture Management's ALEC Position: Q4 2025 in Review

5AM Venture Management sold out of Alector (ALEC) in Q4 2025, closing a stake of 995,841 shares — an estimated $2.95M sold.

5AM Venture Management first reported a position in ALEC in Q4 2024 and held it in 4 quarters. The position peaked at $2.95M in Q3 2025. 131 funds tracked by Wall St. Rank hold ALEC as of Q4 2025.

5AM Venture Management reported no remaining Alector position as of Q4 2025 after selling out during the quarter.
5AM Venture Management sold 995,841 Alector shares in Q4 2025, an estimated $2.95M.
5AM Venture Management first reported a position in Alector in Q4 2024 and held it in 4 quarters.
5AM Venture Management's Alector position peaked at $2.95M in Q3 2025.
131 funds tracked by Wall St. Rank held Alector as of Q4 2025.

Based on 5AM Venture Management's 13F filing for Q4 2025, filed 17 Feb 2026.