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Alector

149 hedge funds and large institutions have $221M invested in Alector in 2025 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 46 increasing their positions, 40 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

139% more call options, than puts

Call options by funds: $1.93M | Put options by funds: $807K

124% more capital invested

Capital invested by funds: $98.7M → $221M (+$123M)

108% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 12

100% more funds holding in top 10

Funds holding in top 10: 36 (+3)

15% more repeat investments, than reductions

Existing positions increased: 46 | Existing positions reduced: 40

10% more funds holding

Funds holding: 136149 (+13)

3.34% more ownership

Funds ownership: 70.51%73.85% (+3.3%)

Holders
149
Holders Change
+13
Holders Change %
+9.56%
% of All Funds
1.96%
Holding in Top 10
6
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
25
Increased
46
Reduced
40
Closed
12
Calls
$1.93M
Puts
$807K
Net Calls
+$1.13M
Net Calls Change
+$915K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$44.9M +$403K +182,960 +1%
BlackRock
2
BlackRock
New York
$21.3M -$1.71M -775,607 -10%
RI
3
RTW Investments
New York
$20.7M +$15.4M +6,990,806 New
Vanguard Group
4
Vanguard Group
Pennsylvania
$17.9M +$103K +46,955 +0.8%
MC
5
Merck & Co
New Jersey
$10.5M
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$7.02M +$446K +202,597 +9%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$6.47M -$5.93M -2,690,232 -55%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$5.51M -$266K -120,810 -6%
State Street
9
State Street
Massachusetts
$5.13M +$54.6K +24,777 +1%
EP
10
Eversept Partners
New York
$4.41M -$1.1M -497,347 -25%
EC
11
Euclidean Capital
New York
$3.87M
Jacobs Levy Equity Management
12
Jacobs Levy Equity Management
New Jersey
$3.64M -$202K -91,908 -7%
Millennium Management
13
Millennium Management
New York
$3.42M +$1.64M +744,224 +181%
Deutsche Bank
14
Deutsche Bank
Germany
$3.16M +$173K +78,468 +8%
DM
15
Deerfield Management
New York
$3.12M
6CM
16
683 Capital Management
New York
$2.96M +$2.2M +1,000,000 New
5VM
17
5AM Venture Management
California
$2.95M
VPC
18
Vestal Point Capital
New York
$2.9M +$6.63K +3,008 +0.3%
D.E. Shaw & Co
19
D.E. Shaw & Co
New York
$2.9M +$978K +444,004 +83%
Renaissance Technologies
20
Renaissance Technologies
New York
$2.81M -$673K -305,700 -24%
Barclays
21
Barclays
United Kingdom
$2.59M +$1.55M +703,580 +414%
DCM
22
DAFNA Capital Management
California
$2.36M -$252K -114,577 -13%
IC
23
Ikarian Capital
Texas
$2.25M -$308K -140,000 -16%
PAM
24
Panagora Asset Management
Massachusetts
$2.19M +$495K +224,613 +43%
Charles Schwab
25
Charles Schwab
California
$2.04M +$92.2K +41,871 +6%

ALEC Hedge Fund Activity: Q3 2025 in Review

149 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Alector (ALEC) for Q3 2025, worth a combined $221M — up 124% from $98.7M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new ALEC positions and 12 closed out — a net gain of 13 holders — while 46 added to existing stakes and 40 trimmed.

The largest buyer was RTW Investments, opening a new position worth an estimated $15.4M. The largest seller was T. Rowe Price Associates, cutting an estimated $5.93M.

  • 149 institutional investors held Alector (ALEC) as of Q3 2025, up from 136 in Q2 2025.
  • Funds reported $221M of Alector stock for Q3 2025, up 124% quarter-over-quarter.
  • 25 funds opened new Alector positions in Q3 2025 and 12 closed out, a net change of +13 holders.
  • The largest Alector buyer in Q3 2025 was RTW Investments, an estimated $15.4M added.
  • The largest Alector seller in Q3 2025 was T. Rowe Price Associates, an estimated $5.93M sold.

Based on aggregated 13F filings for Q3 2025.