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Puma Biotechnology
PBYI

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
USD 381 M – – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
USD 327 M – – –
OrbiMed
3
OrbiMed
New York
USD 160 M -USD 29.4 M -580,500 -20%
Janus Henderson Investors US
4
Janus Henderson Investors US
Colorado
USD 153 M -USD 12.8 M -252,557 -10%
Vanguard Group
5
Vanguard Group
Pennsylvania
USD 134 M +USD 3.77 M +74,579 +4%
Point72 Asset Management
6
Point72 Asset Management
Connecticut
USD 69 M -USD 19.6 M -387,094 -27%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
USD 62.5 M -USD 4.32 M -85,400 -8%
State Street
8
State Street
Massachusetts
USD 61.2 M -USD 7.19 M -142,197 -13%
Wellington Management Group
9
Wellington Management Group
Massachusetts
USD 47.1 M +USD 34.9 M +690,271 +5,468%
Redmile Group
10
Redmile Group
California
USD 44.4 M +USD 33.5 M +662,286 Nuevas
American Century Companies
11
American Century Companies
Missouri
USD 43.7 M +USD 33 M +651,675 Nuevas
BlackRock Institutional Trust
12
BlackRock Institutional Trust
California
USD 42.9 M +USD 2.9 M +57,373 +10%
BlackRock Fund Advisors
13
BlackRock Fund Advisors
California
USD 42 M +USD 1.21 M +23,953 +4%
Millennium Management
14
Millennium Management
New York
USD 40.7 M +USD 28.1 M +556,615 +1,113%
Northern Trust
15
Northern Trust
Illinois
USD 18.5 M +USD 161 k +3,176 +1%
Weatherbie Capital
16
Weatherbie Capital
Massachusetts
USD 17.6 M -USD 945 k -18,699 -7%
Tekla Capital Management
17
Tekla Capital Management
Massachusetts
USD 17.4 M – – –
Bank of America
18
Bank of America
North Carolina
USD 16.7 M -USD 858 k -16,972 -6%
BB Biotech
19
BB Biotech
Switzerland
USD 16.2 M -USD 9.6 M -190,000 -44%
Clough Capital Partners
20
Clough Capital Partners
Massachusetts
USD 15.6 M -USD 683 k -13,500 -5%
Ameriprise
21
Ameriprise
Minnesota
USD 14.4 M +USD 10.8 M +214,192 Nuevas
EverPoint Asset Management
22
EverPoint Asset Management
Connecticut
USD 14.1 M -USD 12.1 M -240,000 -53%
Norges Bank
23
Norges Bank
Norway
USD 12.6 M +USD 3.64 M +71,927 +58%
Geode Capital Management
24
Geode Capital Management
Massachusetts
USD 11.5 M +USD 1.25 M +24,741 +17%
Bank of New York Mellon
25
Bank of New York Mellon
New York
USD 10.6 M +USD 2.35 M +46,525 +42%
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