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PBYI

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
Castleark Management
176
Castleark Management
Illinois
– -USD 6.82 M -68,985 Cerradas
Soros Fund Management
177
Soros Fund Management
New York
– -USD 6.68 M -67,600 Cerradas
Copernicus Capital Management
178
Copernicus Capital Management
California
– -USD 6.5 M -65,742 Cerradas
AG
179
Artal Group
Luxembourg
– -USD 4.94 M -50,000 Cerradas
Rhenman & Partners Asset Management
180
Rhenman & Partners Asset Management
Sweden
– -USD 4.94 M -50,000 Cerradas
Nicholas Investment Partners
181
Nicholas Investment Partners
California
– -USD 4.49 M -45,453 Cerradas
Chartwell Investment Partners
182
Chartwell Investment Partners
Pennsylvania
– -USD 3.86 M -39,098 Cerradas
Crosspoint Capital Strategies
183
Crosspoint Capital Strategies
California
– -USD 3.49 M -35,349 Cerradas
TD Asset Management
184
TD Asset Management
Ontario, Canada
– -USD 3.3 M -33,362 Cerradas
J. Goldman & Co
185
J. Goldman & Co
New York
– -USD 3.15 M -31,829 Cerradas
BCP
186
Berylson Capital Partners
Massachusetts
– -USD 2.45 M -24,800 Cerradas
Eventide Asset Management
187
Eventide Asset Management
Massachusetts
– -USD 1.98 M -20,000 Cerradas
Spark Investment Management
188
Spark Investment Management
New York
– -USD 1.95 M -19,700 Cerradas
Ohio Public Employees Retirement System (OPERS)
189
Ohio Public Employees Retirement System (OPERS)
Ohio
– -USD 1.88 M -19,035 Cerradas
EAM Investors
190
EAM Investors
California
– -USD 1.78 M -17,987 Cerradas
IHM
191
Iguana Healthcare Management
New York
– -USD 1.73 M -17,500 Cerradas
Diametric Capital
192
Diametric Capital
Massachusetts
– -USD 1.71 M -17,278 Cerradas
Sectoral Asset Management
193
Sectoral Asset Management
Quebec, Canada
– -USD 1.49 M -15,050 Cerradas
Jane Street
194
Jane Street
New York
– -USD 1.34 M -13,601 Cerradas
Cambridge Investment Research Advisors
195
Cambridge Investment Research Advisors
Iowa
– -USD 1.25 M -12,632 Cerradas
Sio Capital Management
196
Sio Capital Management
New York
– -USD 1.21 M -12,209 Cerradas
Squarepoint
197
Squarepoint
New York
– -USD 1.05 M -10,626 Cerradas
Pura Vida Investments
198
Pura Vida Investments
New York
– -USD 989 k -10,000 Cerradas
CEP
199
Chicago Equity Partners
Illinois
– -USD 919 k -9,300 Cerradas
Doheny Asset Management
200
Doheny Asset Management
California
– -USD 870 k -8,800 Cerradas
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