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IMNM

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
USD 417 M +USD 70.9 M +3,312,872 +20%
Fidelity Investments
2
Fidelity Investments
Massachusetts
USD 360 M +USD 377 k +17,599 +0.1%
BlackRock
3
BlackRock
New York
USD 187 M +USD 13.6 M +636,818 +8%
State Street
4
State Street
Massachusetts
USD 116 M +USD 2.03 M +94,724 +2%
Wellington Management Group
5
Wellington Management Group
Massachusetts
USD 110 M +USD 10.2 M +478,239 +10%
Redmile Group
6
Redmile Group
California
USD 104 M -USD 13.9 M -647,295 -12%
Primecap Management
7
Primecap Management
California
USD 97.1 M -USD 4.43 M -206,800 -4%
Vanguard Capital Management
8
Vanguard Capital Management
Pennsylvania
USD 96.4 M +USD 2.6 M +121,592 +3%
Driehaus Capital Management
9
Driehaus Capital Management
Illinois
USD 92.1 M +USD 5.27 M +246,238 +6%
ES
10
Enavate Sciences
California
USD 76.6 M – – –
Geode Capital Management
11
Geode Capital Management
Massachusetts
USD 58.4 M +USD 4.16 M +194,225 +8%
Morgan Stanley
12
Morgan Stanley
New York
USD 51 M -USD 9.28 M -433,647 -15%
Silverarc Capital Management
13
Silverarc Capital Management
Massachusetts
USD 42.7 M +USD 3.57 M +166,731 +9%
JP Morgan Chase
14
JP Morgan Chase
New York
USD 39 M -USD 19.9 M -929,288 -33%
T. Rowe Price Associates
15
T. Rowe Price Associates
Maryland
USD 37.6 M -USD 23.2 M -1,085,634 -38%
Sofinnova Investments
16
Sofinnova Investments
California
USD 36.5 M +USD 394 k +18,412 +1%
Readystate Asset Management
17
Readystate Asset Management
Illinois
USD 34 M +USD 6.5 M +303,958 +23%
Goldman Sachs
18
Goldman Sachs
New York
USD 32 M +USD 8.79 M +411,013 +37%
Vanguard Portfolio Management
19
Vanguard Portfolio Management
Pennsylvania
USD 28.6 M +USD 7.32 M +342,004 +34%
Principal Financial Group
20
Principal Financial Group
Iowa
USD 28.6 M -USD 631 k -29,509 -2%
BNP Paribas Asset Management
21
BNP Paribas Asset Management
France
USD 26.5 M +USD 3.26 M +152,439 +14%
Woodline Partners
22
Woodline Partners
California
USD 21.2 M -USD 12.3 M -575,000 -36%
Northern Trust
23
Northern Trust
Illinois
USD 20.5 M +USD 1.48 M +69,200 +8%
Charles Schwab
24
Charles Schwab
California
USD 18.8 M +USD 736 k +34,404 +4%
MetLife Investment Management
25
MetLife Investment Management
New Jersey
USD 18.2 M +USD 17.2 M +803,219 +1,438%
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