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Name Position Handelswert Veränderung
Aktien
Anteils-
änderung
Investor AB
1
Investor AB
Sweden
8,06 Mio. $ – – –
Deerfield Management
2
Deerfield Management
New York
4,83 Mio. $ +4,57 Mio. $ +735.488 +217 %
New Leaf Venture Partners
3
New Leaf Venture Partners
New York
4,67 Mio. $ -2,09 Mio. $ -336.721 -24 %
InterWest Venture Management
4
InterWest Venture Management
California
4,63 Mio. $ – – –
BlackRock
5
BlackRock
New York
3,93 Mio. $ -857.599 $ -138.033 -14 %
Capital Research Global Investors
6
Capital Research Global Investors
California
3,81 Mio. $ -5,23 Mio. $ -842.322 -50 %
Novo Holdings A/S
7
Novo Holdings A/S
Denmark
3,31 Mio. $ +672.433 $ +108.230 +17 %
Polaris Venture Management Co V
8
Polaris Venture Management Co V
Massachusetts
3,29 Mio. $ – – –
Vanguard Group
9
Vanguard Group
Pennsylvania
2,24 Mio. $ +10.898 $ +1.754 +0,4 %
Morgan Stanley
10
Morgan Stanley
New York
1,86 Mio. $ +1,45 Mio. $ +233.994 +129 %
DAFNA Capital Management
11
DAFNA Capital Management
California
1,78 Mio. $ +1,8 Mio. $ +289.525 +273 %
Bellevue Group
12
Bellevue Group
Switzerland
1,46 Mio. $ – – –
Franklin Resources
13
Franklin Resources
California
1,32 Mio. $ -750.897 $ -120.859 -29 %
Silvercrest Asset Management
14
Silvercrest Asset Management
New York
1,28 Mio. $ -303.356 $ -48.826 -15 %
Frontier Capital Management
15
Frontier Capital Management
Massachusetts
1,14 Mio. $ -154.132 $ -24.808 -9 %
State Street
16
State Street
Massachusetts
956.000 $ +43.833 $ +7.055 +3 %
Alambic Investment Management
17
Alambic Investment Management
California
930.000 $ +988.588 $ +159.116 +331 %
Renaissance Technologies
18
Renaissance Technologies
New York
757.000 $ +935.678 $ +150.600 +832 %
Quinn Opportunity Partners
19
Quinn Opportunity Partners
Virginia
691.000 $ +956.746 $ +153.991 Neu
JP Morgan Chase
20
JP Morgan Chase
New York
655.000 $ +322.107 $ +51.844 +55 %
Geode Capital Management
21
Geode Capital Management
Massachusetts
650.000 $ +106.211 $ +17.095 +13 %
Jacobs Levy Equity Management
22
Jacobs Levy Equity Management
New Jersey
646.000 $ +894.336 $ +143.946 Neu
General Electric
23
General Electric
Ohio
633.000 $ -5,4 Mio. $ -868.764 -86 %
Northern Trust
24
Northern Trust
Illinois
629.000 $ -288.389 $ -46.417 -25 %
Bridgeway Capital Management
25
Bridgeway Capital Management
Texas
564.000 $ +218.698 $ +35.200 +39 %