|
1
|
Fidelity Investments
Boston,
Massachusetts
|
1,64 Mrd. $
|
+13,2 Mio. $
|
+44.210
|
+1 %
|
|
|
2
|
|
1,55 Mrd. $
|
+72 Mio. $
|
+240.976
|
+6 %
|
|
|
3
|
Avoro Capital Advisors
New York
|
1,07 Mrd. $
|
–
|
–
|
–
|
|
|
4
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
585 Mio. $
|
+35,3 Mio. $
|
+118.178
|
+8 %
|
|
|
5
|
State Street
Boston,
Massachusetts
|
502 Mio. $
|
+11 Mio. $
|
+36.724
|
+3 %
|
|
|
6
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
461 Mio. $
|
+22,5 Mio. $
|
+75.243
|
+6 %
|
|
|
7
|
Soleus Capital Management
Greenwich,
Connecticut
|
349 Mio. $
|
-63,9 Mio. $
|
-213.833
|
-19 %
|
|
|
8
|
Capital World Investors
Los Angeles,
California
|
289 Mio. $
|
-14 Mio. $
|
-46.877
|
-6 %
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
260 Mio. $
|
+16,4 Mio. $
|
+55.018
|
+9 %
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
255 Mio. $
|
+60,5 Mio. $
|
+202.326
|
+42 %
|
|
|
11
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
247 Mio. $
|
+13,1 Mio. $
|
+43.789
|
+7 %
|
|
|
12
|
Redmile Group
San Francisco,
California
|
235 Mio. $
|
-12,4 Mio. $
|
-41.500
|
-6 %
|
|
|
13
|
William Blair Investment Management
Chicago,
Illinois
|
212 Mio. $
|
+48,7 Mio. $
|
+162.975
|
+40 %
|
|
|
14
|
Frazier Life Sciences Management
Palo Alto,
California
|
179 Mio. $
|
–
|
–
|
–
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
177 Mio. $
|
+2,11 Mio. $
|
+7.048
|
+2 %
|
|
|
16
|
First Trust Advisors
Wheaton,
Illinois
|
121 Mio. $
|
-7,66 Mio. $
|
-25.621
|
-7 %
|
|
|
17
|
|
121 Mio. $
|
+21,9 Mio. $
|
+73.382
|
+29 %
|
|
|
18
|
|
111 Mio. $
|
+25,1 Mio. $
|
+83.892
|
+39 %
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
105 Mio. $
|
+9,36 Mio. $
|
+31.321
|
+12 %
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
97,3 Mio. $
|
+24,7 Mio. $
|
+82.652
|
+46 %
|
|
|
21
|
|
96,3 Mio. $
|
+77,4 Mio. $
|
+259.030
|
Neu
|
|
|
22
|
|
95,4 Mio. $
|
+76,7 Mio. $
|
+256.665
|
Neu
|
|
|
23
|
Bank of America
Charlotte,
North Carolina
|
95,3 Mio. $
|
-1,26 Mio. $
|
-4.216
|
-2 %
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
94,7 Mio. $
|
+3,84 Mio. $
|
+12.842
|
+5 %
|
|
|
25
|
|
87,5 Mio. $
|
+7,89 Mio. $
|
+26.409
|
+13 %
|
|
