|
1
|
Abingworth
London,
United Kingdom
|
51,1 Mio. $
|
–
|
–
|
–
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
50,2 Mio. $
|
+13,7 Mio. $
|
+114.100
|
+40 %
|
|
|
3
|
Jennison Associates
New York
|
32,4 Mio. $
|
-562.583 $
|
-4.697
|
-2 %
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
27,2 Mio. $
|
-4,8 Mio. $
|
-40.087
|
-16 %
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
25 Mio. $
|
-547.971 $
|
-4.575
|
-2 %
|
|
|
6
|
|
21,7 Mio. $
|
-1,89 Mio. $
|
-15.779
|
-8 %
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
20,4 Mio. $
|
+6,68 Mio. $
|
+55.735
|
+53 %
|
|
|
8
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
13,6 Mio. $
|
-1,35 Mio. $
|
-11.231
|
-9 %
|
|
|
9
|
Kingdon Capital Management
New York
|
10,5 Mio. $
|
+4,94 Mio. $
|
+41.250
|
+98 %
|
|
|
10
|
Clough Capital Partners
Boston,
Massachusetts
|
10,3 Mio. $
|
+245.539 $
|
+2.050
|
+3 %
|
|
|
11
|
BlackRock Fund Advisors
San Francisco,
California
|
9,8 Mio. $
|
+1,43 Mio. $
|
+11.917
|
+18 %
|
|
|
12
|
Tekla Capital Management
Boston,
Massachusetts
|
8,8 Mio. $
|
+176.189 $
|
+1.471
|
+2 %
|
|
|
13
|
|
7,94 Mio. $
|
+7,52 Mio. $
|
+62.776
|
Neu
|
|
|
14
|
|
7 Mio. $
|
-14.253 $
|
-119
|
-0,2 %
|
|
|
15
|
Retirement Systems of Alabama
Montgomery,
Alabama
|
6,86 Mio. $
|
–
|
–
|
–
|
|
|
16
|
|
6,21 Mio. $
|
+5,21 Mio. $
|
+43.490
|
+773 %
|
|
|
17
|
Ameriprise
Minneapolis,
Minnesota
|
5,48 Mio. $
|
-877.232 $
|
-7.324
|
-14 %
|
|
|
18
|
Guggenheim Capital
Chicago,
Illinois
|
5,32 Mio. $
|
+1,47 Mio. $
|
+12.294
|
+41 %
|
|
|
19
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
5,05 Mio. $
|
+544.258 $
|
+4.544
|
+13 %
|
|
|
20
|
SAC Capital Advisors
Stamford,
Connecticut
|
4,14 Mio. $
|
-2,92 Mio. $
|
-24.419
|
-43 %
|
|
|
21
|
Redmile Group
San Francisco,
California
|
4,11 Mio. $
|
+3,89 Mio. $
|
+32.485
|
Neu
|
|
|
22
|
|
4,1 Mio. $
|
+431.190 $
|
+3.600
|
+12 %
|
|
|
23
|
Barclays
London,
United Kingdom
|
4,09 Mio. $
|
+3,22 Mio. $
|
+26.916
|
+374 %
|
|
|
24
|
|
3,84 Mio. $
|
-295.844 $
|
-2.470
|
-8 %
|
|
|
25
|
|
3,79 Mio. $
|
–
|
–
|
–
|
|
