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Zymeworks
ZYME

114 hedge funds and large institutions have $694M invested in Zymeworks in 2021 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 43 increasing their positions, 26 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 26

11.52% more ownership

Funds ownership: 79.43% → 90.95% (+12%)

3% more call options, than puts

Call options by funds: $2.41M | Put options by funds: $2.33M

7% less funds holding

Funds holding: 123 → 114 (-9)

24% less first-time investments, than exits

New positions opened: 22 | Existing positions closed: 29

35% less capital invested

Capital invested by funds: $1.07B → $694M (-$376M)

Holders
114
Holders Change
-9
Holders Change %
-7.32%
% of All Funds
1.75%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
22
Increased
43
Reduced
26
Closed
29
Calls
$2.41M
Puts
$2.33M
Net Calls
+$78K
Net Calls Change
-$2.5M

Top Buyers

Rank Fund Capital Flow
1
Bank of America
Bank of America
North Carolina
+$55M
2
Wellington Management Group
Wellington Management Group
Massachusetts
+$47.1M
3
Goldman Sachs
Goldman Sachs
New York
+$46.7M
4
WP
Woodline Partners
California
+$26.2M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
+$15.6M

Top Sellers

Rank Fund Capital Flow
1
PAMS
Pictet Asset Management (Switzerland)
Switzerland
-$51.3M
2
LPC
Lone Pine Capital
Connecticut
-$28.4M
3
AC
Armistice Capital
New York
-$26.6M
4
EAM
Eventide Asset Management
Massachusetts
-$19M
5
CAM
Cormorant Asset Management
Massachusetts
-$7.3M
Name Holding Trade Value Shares
Change 		Change in
Stake
National Bank of Canada
101
National Bank of Canada
Quebec, Canada
$10K +$12.5K +600 New
SOW
102
State of Wyoming
Wyoming
$6K +$646 +31 +9%
DFCM
103
Dark Forest Capital Management
Puerto Rico
$6K +$7.55K +362 New
US Bancorp
104
US Bancorp
Minnesota
$5K -$6.8K -326 -48%
HWM
105
HighMark Wealth Management
Minnesota
$5K – – –
IA
106
IFP Advisors
Florida
$5K – – –
SPIA
107
Steward Partners Investment Advisory
New York
$3K -$146 -7 -4%
AF
108
Allworth Financial
California
$2K – – –
EBA
109
Eagle Bay Advisors
New York
$2K +$2.29K +110 New
TWC
110
TD Waterhouse Canada
Ontario, Canada
$1.98K +$2K +96 New
APA
111
American Portfolios Advisors
New York
$1.67K – – –
ADL
112
Asset Dedication LLC
California
$1K – – –
CA
113
CoreCap Advisors
Michigan
$1K +$375 +18 New
PAMS
114
Pictet Asset Management (Switzerland)
Switzerland
– -$51.3M -1,767,508 Closed
LPC
115
Lone Pine Capital
Connecticut
– -$28.4M -976,735 Closed
B
116
Bailard
California
– -$2.13M -73,200 Closed
AA
117
ALPS Advisors
Colorado
– -$1.65M -56,851 Closed
IHAM
118
Integral Health Asset Management
New York
– -$1.45M -50,000 Closed
JGC
119
J. Goldman & Co
New York
– -$1.45M -49,992 Closed
AAA
120
Affinity Asset Advisors
New York
– -$1.13M -38,814 Closed
VIA
121
Vident Investment Advisory
Georgia
– -$1.13M -38,784 Closed
JF
122
Jump Financial
Illinois
– -$983K -33,841 Closed
GTCM
123
Gyon Technologies Capital Management
New Jersey
– -$980K -33,737 Closed
KJHP
124
K.J. Harrison & Partners
Ontario, Canada
– -$876K -30,000 Closed
GC
125
Guggenheim Capital
Illinois
– -$614K -21,133 Closed
2 3 4
5
6

ZYME Hedge Fund Activity: Q4 2021 in Review

114 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q4 2021, worth a combined $694M — down 35% from $1.07B a quarter earlier.

Sellers outnumbered buyers: 29 funds closed out of ZYME and 22 opened new positions — a net loss of 7 holders — while 26 trimmed existing stakes and 43 added.

The largest buyer was Bank of America, adding an estimated $55M. The largest seller was Pictet Asset Management (Switzerland), exiting entirely with an estimated $51.3M sold.

  • 114 institutional investors held Zymeworks (ZYME) as of Q4 2021, down from 123 in Q3 2021.
  • Funds reported $694M of Zymeworks stock for Q4 2021, down 35% quarter-over-quarter.
  • 22 funds opened new Zymeworks positions in Q4 2021 and 29 closed out, a net change of -7 holders.
  • The largest Zymeworks buyer in Q4 2021 was Bank of America, an estimated $55M added.
  • The largest Zymeworks seller in Q4 2021 was Pictet Asset Management (Switzerland), an estimated $51.3M sold.

Based on aggregated 13F filings for Q4 2021.