Zai Lab
ZLAB
156 hedge funds and large institutions have $1.49B invested in Zai Lab in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 48 increasing their positions, 59 reducing their positions, and 36 closing their positions.
33.21% more ownership
Funds ownership: 5.15% → 38.36% (+33%)
8% less first-time investments, than exits
New positions opened: 33 | Existing positions closed: 36
3% less funds holding
Funds holding: 160 → 156 (-4)
17% less call options, than puts
Call options by funds: $6.06M | Put options by funds: $7.27M
19% less repeat investments, than reductions
Existing positions increased: 48 | Existing positions reduced: 59
24% less capital invested
Capital invested by funds: $1.97B → $1.49B (-$479M)
29% less funds holding in top 10
Funds holding in top 10: 7 → 5 (-2)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RI
RTW Investments
New York
|
+$78.9M |
| 2 |
FLSM
Frazier Life Sciences Management
Palo Alto,
California
|
+$31.5M |
| 3 |
ClearBridge Investments
New York
|
+$24.1M |
| 4 |
NFT
Nan Fung Trinity
Central, Hong Kong,
Hong Kong
|
+$8.88M |
| 5 |
O
OrbiMed
New York
|
+$7.59M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Principal Financial Group
Des Moines,
Iowa
|
-$91.4M |
| 2 |
Morgan Stanley
New York
|
-$77.1M |
| 3 |
Wellington Management Group
Boston,
Massachusetts
|
-$74.6M |
| 4 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$69.5M |
| 5 |
Mirae Asset Global Investments
Seoul,
South Korea
|
-$67.5M |
ZLAB Hedge Fund Activity: Q2 2025 in Review
156 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q2 2025, worth a combined $1.49B — down 24% from $1.97B a quarter earlier.
Sellers outnumbered buyers: 36 funds closed out of ZLAB and 33 opened new positions — a net loss of 3 holders — while 59 trimmed existing stakes and 48 added.
The largest buyer was RTW Investments, adding an estimated $78.9M. The largest seller was Principal Financial Group, cutting an estimated $91.4M.
- 156 institutional investors held Zai Lab (ZLAB) as of Q2 2025, down from 160 in Q1 2025.
- Funds reported $1.49B of Zai Lab stock for Q2 2025, down 24% quarter-over-quarter.
- 33 funds opened new Zai Lab positions in Q2 2025 and 36 closed out, a net change of -3 holders.
- The largest Zai Lab buyer in Q2 2025 was RTW Investments, an estimated $78.9M added.
- The largest Zai Lab seller in Q2 2025 was Principal Financial Group, an estimated $91.4M sold.
Based on aggregated 13F filings for Q2 2025.