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Zai Lab

138 hedge funds and large institutions have $1.19B invested in Zai Lab in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 48 increasing their positions, 46 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

4% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 46

7% less call options, than puts

Call options by funds: $7.24M | Put options by funds: $7.79M

6.9% less ownership

Funds ownership: 38.36%31.47% (-6.9%)

12% less funds holding

Funds holding: 156138 (-18)

20% less capital invested

Capital invested by funds: $1.49B → $1.19B (-$298M)

45% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 38

Holders
138
Holders Change
-18
Holders Change %
-11.54%
% of All Funds
1.81%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
21
Increased
48
Reduced
46
Closed
38
Calls
$7.24M
Puts
$7.79M
Net Calls
-$551K
Net Calls Change
+$657K
Name Holding Trade Value Shares
Change
Change in
Stake
BFM
76
Boothbay Fund Management
New York
$393K +$399K +11,586 New
NSEDCP
77
NJ State Employees Deferred Compensation Plan
New Jersey
$383K
Stifel Financial
78
Stifel Financial
Missouri
$380K -$998 -29 -0.3%
Truist Financial
79
Truist Financial
North Carolina
$377K +$25.6K +743 +7%
AA
80
ABC Arbitrage
France
$352K +$358K +10,388 New
VIA
81
Virtus Investment Advisers
Connecticut
$350K
SG Americas Securities
82
SG Americas Securities
New York
$331K +$336K +9,754 New
JP Morgan Chase
83
JP Morgan Chase
New York
$319K -$13.2K -384 -4%
VPIM
84
Vanguard Personalized Indexing Management
California
$303K -$97.8K -2,840 -24%
QCM
85
Quantinno Capital Management
New York
$293K -$2.17K -63 -0.7%
CUAMC
86
China Universal Asset Management Company
China
$284K -$112K -3,247 -28%
Bank of New York Mellon
87
Bank of New York Mellon
New York
$283K +$28.9K +838 +11%
Citigroup
88
Citigroup
New York
$280K -$8.47K -246 -3%
Cetera Investment Advisers
89
Cetera Investment Advisers
Illinois
$273K +$278K +8,069 New
JRP
90
Jasper Ridge Partners
California
$272K
KWM
91
Kingsview Wealth Management
Oregon
$271K -$35.6K -1,035 -11%
AI
92
Atria Investments
North Carolina
$254K -$19.9K -577 -7%
P
93
&Partners
Tennessee
$240K +$21.7K +631 +10%
PA
94
Profund Advisors
Maryland
$229K +$233K +6,767 New
PAS
95
Park Avenue Securities
New York
$224K +$1.38K +40 +0.6%
OIA
96
OneDigital Investment Advisors
Kansas
$216K +$1.38K +40 +0.6%
PEAK6
97
PEAK6
Illinois
$203K -$51.6K -1,500 -20%
JFG
98
Jefferies Financial Group
New York
$125K -$44.8K -1,300 -26%
IWA
99
Icon Wealth Advisors
Texas
$109K +$1.48K +43 +1%
Pictet Asset Management
100
Pictet Asset Management
Switzerland
$91.5K

ZLAB Hedge Fund Activity: Q3 2025 in Review

138 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q3 2025, worth a combined $1.19B — down 20% from $1.49B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of ZLAB and 21 opened new positions — a net loss of 17 holders — while 46 trimmed existing stakes and 48 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $27.4M. The largest seller was RTW Investments, cutting an estimated $112M.

  • 138 institutional investors held Zai Lab (ZLAB) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $1.19B of Zai Lab stock for Q3 2025, down 20% quarter-over-quarter.
  • 21 funds opened new Zai Lab positions in Q3 2025 and 38 closed out, a net change of -17 holders.
  • The largest Zai Lab buyer in Q3 2025 was T. Rowe Price Associates, an estimated $27.4M added.
  • The largest Zai Lab seller in Q3 2025 was RTW Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q3 2025.