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Zai Lab

138 hedge funds and large institutions have $1.19B invested in Zai Lab in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 48 increasing their positions, 46 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

4% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 46

7% less call options, than puts

Call options by funds: $7.24M | Put options by funds: $7.79M

6.9% less ownership

Funds ownership: 38.36%31.47% (-6.9%)

12% less funds holding

Funds holding: 156138 (-18)

20% less capital invested

Capital invested by funds: $1.49B → $1.19B (-$298M)

45% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 38

Holders
138
Holders Change
-18
Holders Change %
-11.54%
% of All Funds
1.81%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
21
Increased
48
Reduced
46
Closed
38
Calls
$7.24M
Puts
$7.79M
Net Calls
-$551K
Net Calls Change
+$657K
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
51
Dimensional Fund Advisors
Texas
$1.58M +$1.07M +31,113 +200%
MML Investors Services
52
MML Investors Services
Massachusetts
$1.54M +$62.1K +1,805 +4%
BCM
53
Barometer Capital Management
Ontario, Canada
$1.42M +$630K +18,300 +78%
Invesco
54
Invesco
Georgia
$1.31M -$311K -9,045 -19%
WIM
55
WealthPlan Investment Management
Nebraska
$1.25M
DekaBank Deutsche Girozentrale
56
DekaBank Deutsche Girozentrale
Germany
$1.21M
Zurich Cantonal Bank
57
Zurich Cantonal Bank
Switzerland
$1.18M +$368K +10,692 +44%
D.E. Shaw & Co
58
D.E. Shaw & Co
New York
$1.16M -$8.45M -245,371 -88%
Bank of Montreal
59
Bank of Montreal
Ontario, Canada
$1.09M +$77.7K +2,257 +8%
HF
60
HRT Financial
New York
$907K +$174K +5,063 +23%
US Bancorp
61
US Bancorp
Minnesota
$839K +$11.2K +324 +1%
Russell Investments Group
62
Russell Investments Group
United Kingdom
$752K +$1.17K +34 +0.2%
LWAM
63
Legacy Wealth Asset Management
Minnesota
$750K +$5.92K +172 +0.8%
OAM
64
Oppenheimer Asset Management
New York
$737K -$8.26K -240 -1%
Royal Bank of Canada
65
Royal Bank of Canada
Ontario, Canada
$724K +$91.7K +2,664 +14%
GS
66
GTS Securities
New York
$660K +$670K +19,465 New
MGWM
67
Marks Group Wealth Management
Minnesota
$560K +$78.2K +2,270 +16%
AllianceBernstein
68
AllianceBernstein
Tennessee
$560K -$2.37M -68,733 -81%
EAM
69
Erste Asset Management
Austria
$497K
Cerity Partners
70
Cerity Partners
New York
$484K +$516 +15 +0.1%
PCMH
71
Polymer Capital Management (HK)
Hong Kong
$471K +$479K +13,902 New
GCP
72
GSA Capital Partners
United Kingdom
$442K -$500K -14,512 -53%
SAM
73
Sectoral Asset Management
Quebec, Canada
$427K -$112K -3,250 -21%
ICM
74
Infini Capital Management
Hong Kong
$423K +$430K +12,480 New
OAC
75
OMERS Administration Corp
Ontario, Canada
$393K +$399K +11,600 New

ZLAB Hedge Fund Activity: Q3 2025 in Review

138 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q3 2025, worth a combined $1.19B — down 20% from $1.49B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of ZLAB and 21 opened new positions — a net loss of 17 holders — while 46 trimmed existing stakes and 48 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $27.4M. The largest seller was RTW Investments, cutting an estimated $112M.

  • 138 institutional investors held Zai Lab (ZLAB) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $1.19B of Zai Lab stock for Q3 2025, down 20% quarter-over-quarter.
  • 21 funds opened new Zai Lab positions in Q3 2025 and 38 closed out, a net change of -17 holders.
  • The largest Zai Lab buyer in Q3 2025 was T. Rowe Price Associates, an estimated $27.4M added.
  • The largest Zai Lab seller in Q3 2025 was RTW Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q3 2025.