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Zai Lab

138 hedge funds and large institutions have $1.19B invested in Zai Lab in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 48 increasing their positions, 46 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

4% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 46

7% less call options, than puts

Call options by funds: $7.24M | Put options by funds: $7.79M

6.9% less ownership

Funds ownership: 38.36%31.47% (-6.9%)

12% less funds holding

Funds holding: 156138 (-18)

20% less capital invested

Capital invested by funds: $1.49B → $1.19B (-$298M)

45% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 38

Holders
138
Holders Change
-18
Holders Change %
-11.54%
% of All Funds
1.81%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
21
Increased
48
Reduced
46
Closed
38
Calls
$7.24M
Puts
$7.79M
Net Calls
-$551K
Net Calls Change
+$657K
Name Holding Trade Value Shares
Change
Change in
Stake
HWAM
26
Hennion & Walsh Asset Management
New Jersey
$5.42M -$277K -8,053 -5%
Schroder Investment Management Group
27
Schroder Investment Management Group
United Kingdom
$5.17M +$4.63M +134,362 +592%
Northern Trust
28
Northern Trust
Illinois
$4.95M -$482 -14 -0%
Bank of America
29
Bank of America
North Carolina
$4.83M -$254K -7,370 -5%
State Street
30
State Street
Massachusetts
$4.62M -$82.1K -2,386 -2%
LP
31
LMR Partners
United Kingdom
$4.5M +$3.05M +88,598 +201%
PFM
32
Privium Fund Management
Netherlands
$4.48M
TD Asset Management
33
TD Asset Management
Ontario, Canada
$4.12M +$3.35M +97,400 +404%
Morgan Stanley
34
Morgan Stanley
New York
$4.06M -$5.83M -169,221 -59%
Mirae Asset Global Investments
35
Mirae Asset Global Investments
South Korea
$3.56M +$938K +27,242 +35%
Balyasny Asset Management
36
Balyasny Asset Management
Illinois
$3.54M +$2.53M +73,578 +239%
Principal Financial Group
37
Principal Financial Group
Iowa
$3.53M -$7.85K -228 -0.2%
IAMH
38
IvyRock Asset Management (HK)
Hong Kong
$3.22M +$3.27M +94,879 New
DA
39
DCF Advisers
Connecticut
$3.12M +$34.4K +1,000 +1%
LPL Financial
40
LPL Financial
California
$2.88M +$1.83M +53,246 +167%
Goldman Sachs
41
Goldman Sachs
New York
$2.79M -$2.14M -62,141 -43%
Manulife (Manufacturers Life Insurance)
42
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.34M +$1.68M +48,791 +240%
AIM
43
AXA Investment Managers
France
$2.23M +$2.27M +65,814 New
LCAM
44
Long Corridor Asset Management
Hong Kong
$2.23M +$2.27M +65,800 New
NIM
45
NEOS Investment Management
Connecticut
$2.1M +$111K +3,232 +5%
TE
46
Tema ETFs
New York
$2.1M +$111K +3,232 +5%
Marshall Wace
47
Marshall Wace
United Kingdom
$2.08M +$1.27M +36,946 +151%
AA
48
ALPS Advisors
Colorado
$1.78M -$282K -8,182 -13%
Geode Capital Management
49
Geode Capital Management
Massachusetts
$1.71M -$205K -5,946 -11%
BCI
50
Brinker Capital Investments
Pennsylvania
$1.64M +$2.89K +84 +0.2%

ZLAB Hedge Fund Activity: Q3 2025 in Review

138 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q3 2025, worth a combined $1.19B — down 20% from $1.49B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of ZLAB and 21 opened new positions — a net loss of 17 holders — while 46 trimmed existing stakes and 48 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $27.4M. The largest seller was RTW Investments, cutting an estimated $112M.

  • 138 institutional investors held Zai Lab (ZLAB) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $1.19B of Zai Lab stock for Q3 2025, down 20% quarter-over-quarter.
  • 21 funds opened new Zai Lab positions in Q3 2025 and 38 closed out, a net change of -17 holders.
  • The largest Zai Lab buyer in Q3 2025 was T. Rowe Price Associates, an estimated $27.4M added.
  • The largest Zai Lab seller in Q3 2025 was RTW Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q3 2025.