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ZBIO

Zenas BioPharma

67 hedge funds and large institutions have $257M invested in Zenas BioPharma in 2025 Q1 according to their latest regulatory filings, with 12 funds opening new positions, 15 increasing their positions, 20 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more first-time investments, than exits

New positions opened: 12 | Existing positions closed: 10

3% more funds holding

Funds holding: 6567 (+2)

1.89% more ownership

Funds ownership: 75.85%77.75% (+1.9%)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

1% less capital invested

Capital invested by funds: $260M → $257M (-$2.92M)

25% less repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 20

Holders
67
Holders Change
+2
Holders Change %
+3.08%
% of All Funds
0.9%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
12
Increased
15
Reduced
20
Closed
10
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
SOCM
1
SR One Capital Management
Pennsylvania
$38.8M
ES
2
Enavate Sciences
California
$29.7M
Fidelity Investments
3
Fidelity Investments
Massachusetts
$22.5M +$8.38M +1,070,656 +60%
NMC
4
NEA Management Company
Maryland
$20.7M
NHAS
5
Novo Holdings A/S
Denmark
$17.5M +$4.81M +614,967 +38%
FFM
6
Fairmount Funds Management
Pennsylvania
$15M
NA
7
NVP Associates
California
$14.5M
DM
8
Deerfield Management
New York
$12.3M
VC
9
Vivo Capital
California
$9.35M
Federated Hermes
10
Federated Hermes
Pennsylvania
$9.15M
ACH
11
ArrowMark Colorado Holdings
Colorado
$8.67M +$3.68M +469,700 +75%
BlackRock
12
BlackRock
New York
$8.01M +$59.1K +7,552 +0.8%
Vanguard Group
13
Vanguard Group
Pennsylvania
$7.71M -$26.7K -3,417 -0.3%
RSCM
14
Rock Springs Capital Management
Maryland
$6.94M
Wellington Management Group
15
Wellington Management Group
Massachusetts
$6.9M -$2.05M -261,666 -23%
PBPIA
16
Pivotal bioVenture Partners Investment Advisor
California
$5.82M
T. Rowe Price Associates
17
T. Rowe Price Associates
Maryland
$4.09M +$50K +6,386 +1%
EP
18
Eversept Partners
New York
$3.52M +$2.14M +273,485 +159%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$2.82M +$65.7K +8,396 +2%
CCM
20
Catalio Capital Management
New York
$2.33M +$845K +107,964 +58%
State Street
21
State Street
Massachusetts
$2.1M +$428K +54,694 +26%
Schroder Investment Management Group
22
Schroder Investment Management Group
United Kingdom
$1.34M -$61.9K -7,905 -5%
Northern Trust
23
Northern Trust
Illinois
$950K -$31.4K -4,008 -3%
Charles Schwab
24
Charles Schwab
California
$918K -$19.7K -2,520 -2%
SCM
25
Superstring Capital Management
New York
$882K

ZBIO Hedge Fund Activity: Q1 2025 in Review

67 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Zenas BioPharma (ZBIO) for Q1 2025, worth a combined $257M — down 1.1% from $260M a quarter earlier.

Buyers outnumbered sellers: 12 funds opened new ZBIO positions and 10 closed out — a net gain of 2 holders — while 15 added to existing stakes and 20 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $8.38M. The largest seller was Perceptive Advisors, exiting entirely with an estimated $6.09M sold.

  • 67 institutional investors held Zenas BioPharma (ZBIO) as of Q1 2025, up from 65 in Q4 2024.
  • Funds reported $257M of Zenas BioPharma stock for Q1 2025, down 1.1% quarter-over-quarter.
  • 12 funds opened new Zenas BioPharma positions in Q1 2025 and 10 closed out, a net change of +2 holders.
  • The largest Zenas BioPharma buyer in Q1 2025 was Fidelity Investments, an estimated $8.38M added.
  • The largest Zenas BioPharma seller in Q1 2025 was Perceptive Advisors, an estimated $6.09M sold.

Based on aggregated 13F filings for Q1 2025.