We are live on ! Find out more
ZBIO

Zenas BioPharma

139 hedge funds and large institutions have $1.1B invested in Zenas BioPharma in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 57 increasing their positions, 17 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

235% more repeat investments, than reductions

Existing positions increased: 57 | Existing positions reduced: 17

89% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 27

29% more call options, than puts

Call options by funds: $3.48M | Put options by funds: $2.71M

19.13% more ownership

Funds ownership: 77.43%96.56% (+19%)

18% more funds holding

Funds holding: 118139 (+21)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

27% less capital invested

Capital invested by funds: $1.5B → $1.1B (-$407M)

Holders
139
Holders Change
+21
Holders Change %
+17.8%
% of All Funds
1.71%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
51
Increased
57
Reduced
17
Closed
27
Calls
$3.48M
Puts
$2.71M
Net Calls
+$774K
Net Calls Change
-$2.57M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$178M +$30.9M +1,377,745 +18%
SOCM
2
SR One Capital Management
Pennsylvania
$98.5M
NMC
3
NEA Management Company
Maryland
$78.7M +$11.2M +500,000 +14%
ES
4
Enavate Sciences
California
$76.6M
Federated Hermes
5
Federated Hermes
Pennsylvania
$61.1M +$9.24M +411,453 +15%
PCH
6
Polar Capital Holdings
United Kingdom
$49.8M +$33.5M +1,490,835 +141%
Capital International Investors
7
Capital International Investors
California
$47.6M +$54.6M +2,434,000 New
FFM
8
Fairmount Funds Management
Pennsylvania
$46.1M +$3.37M +150,000 +7%
BlackRock
9
BlackRock
New York
$39.8M +$6.06M +270,030 +15%
NA
10
NVP Associates
California
$35.9M
AllianceBernstein
11
AllianceBernstein
Tennessee
$32.6M +$19.7M +878,971 +4,790%
State Street
12
State Street
Massachusetts
$28.8M +$23.2M +1,032,629 +236%
Wellington Management Group
13
Wellington Management Group
Massachusetts
$24.4M +$8.77M +390,719 +46%
VCM
14
Vanguard Capital Management
Pennsylvania
$24.3M +$28M +1,245,391 New
SCM
15
Silverarc Capital Management
Massachusetts
$22.2M +$25.5M +1,135,935 New
EC
16
EcoR1 Capital
California
$15.4M
Balyasny Asset Management
17
Balyasny Asset Management
Illinois
$13M +$10.6M +473,917 +245%
ACH
18
ArrowMark Colorado Holdings
Colorado
$12.9M -$2.07M -92,252 -12%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$12.8M +$1.51M +67,392 +11%
PBPIA
20
Pivotal bioVenture Partners Investment Advisor
California
$11.6M
WP
21
Woodline Partners
California
$11.5M +$13.3M +590,525 New
GPP
22
Great Point Partners
Connecticut
$10.2M +$11.8M +524,066 New
RSCM
23
Rock Springs Capital Management
Maryland
$9.82M
Marshall Wace
24
Marshall Wace
United Kingdom
$9.81M +$11.1M +494,828 +6,969%
Millennium Management
25
Millennium Management
New York
$9.32M +$9.6M +427,658 +870%

ZBIO Hedge Fund Activity: Q1 2026 in Review

139 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Zenas BioPharma (ZBIO) for Q1 2026, worth a combined $1.1B — down 27% from $1.5B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new ZBIO positions and 27 closed out — a net gain of 24 holders — while 57 added to existing stakes and 17 trimmed.

The largest buyer was Capital International Investors, opening a new position worth an estimated $54.6M. The largest seller was Novo Holdings A/S, exiting entirely with an estimated $52.6M sold.

  • 139 institutional investors held Zenas BioPharma (ZBIO) as of Q1 2026, up from 118 in Q4 2025.
  • Funds reported $1.1B of Zenas BioPharma stock for Q1 2026, down 27% quarter-over-quarter.
  • 51 funds opened new Zenas BioPharma positions in Q1 2026 and 27 closed out, a net change of +24 holders.
  • The largest Zenas BioPharma buyer in Q1 2026 was Capital International Investors, an estimated $54.6M added.
  • The largest Zenas BioPharma seller in Q1 2026 was Novo Holdings A/S, an estimated $52.6M sold.

Based on aggregated 13F filings for Q1 2026.