|
1
|
|
$11.9M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$11.4M
|
–
|
–
|
–
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$11.2M
|
-$115K
|
-291
|
-1%
|
|
|
4
|
|
$8.98M
|
+$3.3M
|
+8,347
|
+55%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$7.54M
|
+$171K
|
+432
|
+2%
|
|
|
6
|
Deerfield Management
New York
|
$7.17M
|
-$16.6K
|
-42
|
-0.2%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.89M
|
+$252K
|
+637
|
+4%
|
|
|
8
|
RA Capital Management
Boston,
Massachusetts
|
$6.08M
|
-$5.06M
|
-12,776
|
-44%
|
|
|
9
|
NEA Management Company
Timonium,
Maryland
|
$4.24M
|
–
|
–
|
–
|
|
|
10
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$3.96M
|
–
|
–
|
–
|
|
|
11
|
SV Health Investors
Boston,
Massachusetts
|
$3.96M
|
–
|
–
|
–
|
|
|
12
|
New Leaf Venture Partners
New York
|
$3.62M
|
–
|
–
|
–
|
|
|
13
|
Millennium Management
New York
|
$2.4M
|
+$488K
|
+1,233
|
+24%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$1.8M
|
+$806K
|
+2,036
|
+75%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$1.46M
|
+$5.94K
|
+15
|
+0.4%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$1.45M
|
+$1.16M
|
+2,937
|
+338%
|
|
|
17
|
Sphera Funds Management
Tel Aviv,
Israel
|
$602K
|
–
|
–
|
–
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$409K
|
+$269K
|
+679
|
+172%
|
|
|
19
|
Charles Schwab
San Francisco,
California
|
$400K
|
+$137K
|
+345
|
+49%
|
|
|
20
|
Oxford Asset Management
Oxford,
United Kingdom
|
$360K
|
-$1.19K
|
-3
|
-0.3%
|
|
|
21
|
Bank of New York Mellon
New York
|
$344K
|
+$173K
|
+436
|
+94%
|
|
|
22
|
Wells Fargo
San Francisco,
California
|
$292K
|
+$153K
|
+387
|
+102%
|
|
|
23
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$259K
|
+$112K
|
+284
|
+72%
|
|
|
24
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$235K
|
+$102K
|
+259
|
+72%
|
|
|
25
|
|
$189K
|
-$227K
|
-573
|
-54%
|
|
