|
1
|
|
$14M
|
+$10.6M
|
+20,833
|
+201%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$13.5M
|
+$15.2M
|
+30,000
|
New
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$13.4M
|
+$10.8M
|
+21,255
|
+252%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$12.9M
|
+$14.6M
|
+28,713
|
New
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$8.71M
|
+$9.84M
|
+19,350
|
New
|
|
|
6
|
Deerfield Management
New York
|
$8.47M
|
+$9.57M
|
+18,833
|
New
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.84M
|
+$7.4M
|
+14,551
|
+506%
|
|
|
8
|
|
$6.85M
|
+$7.06M
|
+13,888
|
+1,045%
|
|
|
9
|
NEA Management Company
Timonium,
Maryland
|
$5M
|
–
|
–
|
–
|
|
|
10
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$4.67M
|
–
|
–
|
–
|
|
|
11
|
SV Health Investors
Boston,
Massachusetts
|
$4.67M
|
–
|
–
|
–
|
|
|
12
|
New Leaf Venture Partners
New York
|
$4.28M
|
+$4.83M
|
+9,500
|
New
|
|
|
13
|
Millennium Management
New York
|
$2.27M
|
+$2.57M
|
+5,055
|
New
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$1.71M
|
+$1.71M
|
+3,373
|
+784%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.21M
|
+$1.07M
|
+2,108
|
+357%
|
|
|
16
|
Sphera Funds Management
Tel Aviv,
Israel
|
$711K
|
+$803K
|
+1,580
|
New
|
|
|
17
|
First Eagle Investment Management
New York
|
$536K
|
+$254K
|
+500
|
+72%
|
|
|
18
|
|
$480K
|
+$543K
|
+1,068
|
New
|
|
|
19
|
Oxford Asset Management
Oxford,
United Kingdom
|
$426K
|
+$481K
|
+946
|
New
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$392K
|
+$442K
|
+869
|
New
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$317K
|
+$357K
|
+703
|
New
|
|
|
22
|
Bank of New York Mellon
New York
|
$210K
|
+$237K
|
+466
|
New
|
|
|
23
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$178K
|
+$201K
|
+396
|
New
|
|
|
24
|
Nuveen
Charlotte,
North Carolina
|
$177K
|
+$200K
|
+394
|
New
|
|
|
25
|
Wells Fargo
San Francisco,
California
|
$170K
|
+$185K
|
+363
|
+2,420%
|
|
