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Xenon Pharmaceuticals
XENE

Overview Fund Activity

206 hedge funds and large institutions have $2.58B invested in Xenon Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 68 increasing their positions, 73 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
206
Holders Change
-3
Holders Change %
-1.44%
% of All Funds
2.8%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.19%
New
20
Increased
68
Reduced
73
Closed
23
Calls
$14.8M
Puts
$6.93M
Net Calls
+$7.9M
Net Calls Change
+$3.62M

Top Buyers

1
DTC
Deep Track Capital
Connecticut
+$27.9M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$25.6M
3
LGM
Logos Global Management
California
+$21.8M
4
Capital International Investors
Capital International Investors
California
+$18.2M
5
VPC
Vestal Point Capital
New York
+$16.4M

Top Sellers

1
BBA
Baker Bros. Advisors
New York
-$21.7M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$21.5M
3
FLAM
First Light Asset Management
Minnesota
-$17.9M
4
CC
Commodore Capital
New York
-$13.9M
5
Federated Hermes
Federated Hermes
Pennsylvania
-$10.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
AssetMark Inc
126
AssetMark Inc
California
$669K -$55.4K -1,651 -8%
SMH
127
Sanders Morris Harris
Texas
$659K – – –
Barclays
128
Barclays
United Kingdom
$646K +$38.3K +1,143 +6%
Zurich Cantonal Bank
129
Zurich Cantonal Bank
Switzerland
$636K -$10.7K -318 -2%
ASRS
130
Arizona State Retirement System
Arizona
$623K -$2.92K -87 -0.5%
PCM
131
Prelude Capital Management
New York
$613K – – –
Teacher Retirement System of Texas
132
Teacher Retirement System of Texas
Texas
$585K -$55.2K -1,644 -9%
BC
133
BIT Capital
Germany
$582K -$1.23M -36,576 -68%
OQS
134
Occudo Quantitative Strategies
Florida
$582K +$190K +5,534 +48%
CIBC World Market
135
CIBC World Market
Ontario, Canada
$548K -$117K -3,500 -18%
DMKJ
136
David M. Knott Jr
$532K -$168K -5,000 -24%
OPS
137
Orion Portfolio Solutions
Nebraska
$521K +$70.3K +2,095 +16%
BCI
138
Brinker Capital Investments
Pennsylvania
$521K +$70.3K +2,095 +16%
CUAMC
139
China Universal Asset Management Company
China
$515K -$27.3K -813 -5%
AAM
140
Advisors Asset Management
Colorado
$479K +$41.4K +1,233 +9%
KK
141
KLP Kapitalforvaltning
Norway
$429K – – –
Verition Fund Management
142
Verition Fund Management
Connecticut
$420K +$141K +4,211 +51%
YIH
143
Y-Intercept (HK)
Hong Kong
$401K +$401K +11,949 New
FRM
144
Fox Run Management
Connecticut
$382K +$92.3K +2,751 +32%
EWM
145
Elmwood Wealth Management
California
$369K – – –
SACTSONJ
146
Supplemental Annuity Collective Trust (SACT) of New Jersey
New Jersey
$369K – – –
Public Employees Retirement Association of Colorado
147
Public Employees Retirement Association of Colorado
Colorado
$357K – – –
ACM
148
Aquatic Capital Management
Illinois
$353K +$75.5K +2,251 +27%
SCM
149
Silverarc Capital Management
Massachusetts
$340K +$340K +10,121 New
LCM
150
Legato Capital Management
California
$323K +$323K +9,622 New
4 5
6
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